Evidence map›Paper›PMID 26062899›Full record

ArticleReproductive health2015

Lost to follow-up among pregnant women in a multi-site community based maternal and newborn health registry: a prospective study.

Irene Marete, Constance Tenge, Carolyne Chemweno, Sherri Bucher, Omrana Pasha, Umesh Y Ramadurg, Shivanand C Mastiholi, Melody Chiwila, Archana Patel, Fernando Althabe and 11 more

Registry-linked trialAbstract readMulticenter Study
In one paragraph

Article in Reproductive health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01073475 (Global Network for Women's and Children's Health Research Maternal Newborn Health Registry), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01073475 recruitingnot on this map

Global Network for Women's and Children's Health Research Maternal Newborn Health Registry

TypeobservationalSponsorNICHD Global Network for Women's and Children's HealthRan2008 to 2030Enrolled950,000ConditionsPregnancy Outcome Trends in Low-resource Geographic AreasArmsThere is no intervention associated with the parent MNHR study. For the MNHR COVID sub-study, participants will be asked to provide a blood specimen at or near delivery.
3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Trial
  2. Article
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  4. Article
  5. Observational
  6. Article
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  12. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Irene Marete
Constance Tenge
Carolyne Chemweno
Sherri Bucher
Omrana Pasha
Umesh Y Ramadurg
Shivanand C Mastiholi
Melody Chiwila
Archana Patel
Fernando Althabe
Ana Garces
Janet L Moore
Edward A Liechty
Richard J Derman
Patricia L Hibberd
K Hambidge
Robert L Goldenberg
Waldemar A Carlo
Marion Koso-Thomas
Elizabeth M McClure
Fabian Esamai

Funding

Zika in Pregnancy Supplemental Funding requestU01HD040636 · NICHD · RESEARCH TRIANGLE INSTITUTE · PI MCCLURE, ELIZABETH M · 2001 to 2017
$37.5M
UAB/AKU Global Network Research UnitU01HD040607 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GOLDENBERG, ROBERT L · 2001 to 2012
$8.5M
Evidence-Based Global Health Interventions for Mothers and Children, ArgentinaU01HD040477 · NICHD · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI BUEKENS, PIERRE · 2001 to 2013
$5.6M
Boston University/Lata Medical Research Foundation Global Network for Women's Children's Health Research UnitUG1HD078439 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Patricia L Hibberd · 2018 to 2026
$5.5M
Nutrition-specific interventions to improve long-term maternal-child health outcomesUG1HD076474 · NICHD · UNIVERSITY OF COLORADO DENVER · PI Edwin Jose Asturias, NANCY F KREBS · 2018 to 2026
$5.4M
The Global Network and Preconception Maternal NutritionU10HD076474 · NICHD · UNIVERSITY OF COLORADO DENVER · PI HAMBIDGE, K MICHAEL, KREBS, NANCY F · 2013 to 2017
$5.1M
Global Network for Women's and Children's Health ResearchU10HD076461 · NICHD · INDIANA UNIVERSITY INDIANAPOLIS · PI LIECHTY, EDWARD A. · 2013 to 2017
$4.1M
CCHS-JNMC Global Network for Women's & Children's Health Research UnitU10HD076457 · NICHD · THOMAS JEFFERSON UNIVERSITY · PI DERMAN, RICHARD J · 2013 to 2017
$3.7M
Heart Rate Detection during Resuucitation to Reduce Early Neonatal MortalityU10HD078437 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CARLO FONT, WALDEMAR A. · 2013 to 2017
$3.3M
Global Network for Women's and Children's Health ResearchUG1HD076461 · NICHD · INDIANA UNIVERSITY INDIANAPOLIS · PI BUCHER, SHERRI LYNN, SZYLD, EDGARDO GABRIEL · 2018 to 2023
$3.2M
Columbia University/Aga Khan University Global Network Research UnitU10HD078438 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GOLDENBERG, ROBERT L · 2013 to 2017
$3.2M
Maternal and Child Health Benefits from Reducing Household Air PollutionU10HD078439 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI HIBBERD, PATRICIA L · 2013 to 2017
$3.1M
NICHD NIH HHS U01 HD040477NICHD NIH HHS U01 HD040607NICHD NIH HHS U01HD040636NICHD NIH HHS U10 HD076457NICHD NIH HHS U10HD076457NICHD NIH HHS U10 HD076461NICHD NIH HHS U10HD076461NICHD NIH HHS U10HD076465NICHD NIH HHS U10 HD076474NICHD NIH HHS U10HD076474NICHD NIH HHS U10 HD078437NICHD NIH HHS U10HD078437NICHD NIH HHS U10 HD078438NICHD NIH HHS U10HD078438NICHD NIH HHS U10 HD078439NICHD NIH HHS U10HD078439NICHD NIH HHS UG1 HD076461NICHD NIH HHS UG1 HD076474NICHD NIH HHS UG1 HD078439
6 · The paper itself

Abstract

backgroundIt is important when conducting epidemiologic studies to closely monitor lost to follow up (LTFU) rates. A high LTFU rate may lead to incomplete study results which in turn can introduce bias to the trial or study, threatening the validity of the findings. There is scarce information on LTFU in prospective community-based perinatal epidemiological studies. This paper reports the rates of LTFU, describes socio-demographic characteristics, and pregnancy/delivery outcomes of mothers LTFU in a large community-based pregnancy registry study.

methodsData were from a prospective, population-based observational study of the Global Network for Women's and Children's Health Research Maternal Newborn Health Registry (MNHR). This is a multi-centre, international study in which pregnant women were enrolled in mid-pregnancy, followed through parturition and 42 days post-delivery. Risk for LTFU was calculated within a 95%CI.

resultsA total of 282,626 subjects were enrolled in this study, of which 4,893 were lost to follow-up. Overall, there was a 1.7% LTFU to follow up rate. Factors associated with a higher LTFU included mothers who did not know their last menstrual period (RR 2.2, 95% CI 1.1, 4.4), maternal age of < 20 years (RR 1.2, 95% CI 1.1, 1.3), women with no formal education (RR 1.2, 95% CI 1.1, 1.4), and attending a government clinic for antenatal care (RR 2.0, 95% CI 1.4, 2.8). Post-natal factors associated with a higher LTFU rate included a newborn with feeding problems (RR 1.6, 94% CI 1.2, 2.2).

conclusionsThe LTFU rate in this community-based registry was low (1.7%). Maternal age, maternal level of education, pregnancy status at enrollment and using a government facility for ANC are factors associated with being LTFU. Strategies to ensure representation and high retention in community studies are important to informing progress toward public health goals.

trial registrationRegistration at the Clinicaltrials.gov (ID# NCT01073475).

Indexed as

AdolescentAdultDelivery, ObstetricEducational StatusFemaleFollow-Up StudiesHumansInfant HealthInfant, NewbornLost to Follow-UpMaternal AgeMaternal HealthPatient Acceptance of Health CarePregnancyPregnancy OutcomePrenatal Care

Identifiers

PMID26062899
PMCPMC4464022

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.