Evidence map›Paper›PMID 26062496›Full record

ArticleNature2015

Reproducibility: use mouse biobanks or lose them.

Kent Lloyd, Craig Franklin, Cat Lutz, Terry Magnuson

Abstract read
In one paragraph

Article in Nature, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. A quality framework for cryopreserved rodent disease models: INFRAFRONTIER quality principles in EMMA archiving and distribution.Mammalian genome : official journal of the International Mammalian Genome Society · 2025
    Review
  2. Article
  3. Article
  4. The mutant mouse resource and research center (MMRRC) consortium: the US-based public mouse repository system.Mammalian genome : official journal of the International Mammalian Genome Society · 2024
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Importing genetically altered animals: ensuring quality.Mammalian genome : official journal of the International Mammalian Genome Society · 2022
    Review
  11. Article
  12. Article
  13. Differences in bone structure and unloading-induced bone loss between C57BL/6N and C57BL/6J mice.Mammalian genome : official journal of the International Mammalian Genome Society · 2017
    Article
  14. Sharing mutations: are biobanks still required in the post-CRISPR/Cas9 era?Mammalian genome : official journal of the International Mammalian Genome Society · 2017
    Review
  15. Article
  16. INFRAFRONTIER: a European resource for studying the functional basis of human disease.Mammalian genome : official journal of the International Mammalian Genome Society · 2016
    Review
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kent LloydMutant Mouse Resource and Research Center (MMRRC) at the University of California, Davis, California, USA.
Craig FranklinMMRRC at the University of Missouri, Columbia, Missouri, USA.
Cat LutzMMRRC at the Jackson Laboratory in Bar Harbor, Maine, USA.
Terry MagnusonMMRRC at the University of North Carolina at Chapel Hill, North Carolina, USA.

Funding

KOMP2-Phase3 Production and Phenotyping by the DTCC Consortium TCP Transfer to UC DavisUM1OD023221 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KC KENT LLOYD · 2016 to 2026
$45.7M
UCD Mutant Mouse Regional Resource CenterU42OD012210 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KC KENT LLOYD · 2012 to 2026
$29.2M
Resource Section - Core 001U42OD010924 · OD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI TERRY R MAGNUSON · 2012 to 2026
$24.5M
The Mutant Mouse Resource and Research Center at The Jackson LaboratoryU42OD010921 · OD · JACKSON LABORATORY · PI LAURA G REINHOLDT · 2012 to 2026
$21.4M
KOMP Phase II Mouse Production and CryopreservationU42OD011175 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LLOYD, KC KENT · 2012 to 2015
$18.9M
KOMP Phase II Mouse PhenotypingU54HG006364 · NHGRI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LLOYD, KC KENT · 2011 to 2015
$16.3M
KOMP PHASE II MOUSE PRODUCTION AND CRYOPRESERVATION: AIDSU42RR033193 · NCRR · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LLOYD, KC KENT · 2011 to 2011
$4.1M
Mouse Metabolic Phenotyping Center (MMPC) at UC DavisU24DK092993 · NIDDK · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LLOYD, KC KENT · 2011 to 2015
$4.1M
NCRR NIH HHS U42 RR033193NHGRI NIH HHS U54 HG006364NIDDK NIH HHS U24 DK092993NIH HHS U42 OD010921NIH HHS U42 OD010924NIH HHS U42 OD011175NIH HHS U42 OD012210NIH HHS UM1 OD023221
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MiceAnimalsBiological Specimen BanksDisease Models, AnimalDNA Mutational AnalysisGenetic TestingGenomeHumansMice, Inbred C57BLMicrobiotaMutationQuality ControlReproducibility of Results

Identifiers

PMID26062496
PMCPMC4636083

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.