Evidence map›Paper›PMID 26062126›Full record

ArticleInternational psychogeriatrics2015

A consensus guideline for antipsychotic drug use for dementia in care homes. Bridging the gap between scientific evidence and clinical practice.

Sytse U Zuidema, Alice Johansson, Geir Selbaek, Matt Murray, Alistair Burns, Clive Ballard, Raymond T C M Koopmans

Abstract read
In one paragraph

Article in International psychogeriatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
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  3. Review
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  7. Nursing staff's experiences of how weighted blankets influence resident's in nursing homes expressions of health.International journal of qualitative studies on health and well-being · 2022
    Article
  8. Article
  9. Article
  10. In utero exposure to antipsychotic medication and psychiatric outcomes in the offspring.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Article
  11. Review
  12. Article
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  14. Article
  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sytse U ZuidemaDepartment of General Practice,University Medical Center Groningen,University of Groningen,Groningen,the Netherlands.
Alice JohanssonDepartment of Primary and Community Care,Centre for Family Medicine,Geriatric Care and Public Health,Radboud University Medical Centre,Nijmegen,the Netherlands.
Geir SelbaekNorwegian National Advisory Unit of Ageing and Health,Vestfold Hospital Trust,Tønsberg,Norway;Centre for Old Age Psychiatry Research,Innlandet Hospital Trust,Ottestad,Norway;Institute of Clinical Medicine,Campus AHUS,University of Oslo,Norway.
Matt MurrayUK Alzheimer's Society,London,UK.
Alistair BurnsFaculty of Medical and Human Sciences,Institute of Brain,Behaviour and Mental Health,The University of Manchester,UK.
Clive BallardWolfson Centre for Age-Related Diseases,Kings College London,UK.
Raymond T C M KoopmansDepartment of Primary and Community Care,Centre for Family Medicine,Geriatric Care and Public Health,Radboud University Medical Centre,Nijmegen,the NetherlandsandJoachim & Anna,center for specialized geriatric care,Nijmegen,the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo produce a practice guideline that includes a set of detailed consensus principles regarding the prescription of antipsychotics (APs) amongst people with dementia living in care homes.

methodsWe used a modified Delphi consensus procedure with three rounds, where we actively specified and optimized statements throughout the process, utilizing input from four focus groups, carried out in UK, Norway, and the Netherlands. This was done to identify relevant themes and a set of statement that experts agreed upon using the Research and Development/University of California at Los Angeles (RAND/UCLA) methodology.

resultsA total of 72 scientific and clinical experts and 14 consumer experts reached consensus upon 150 statements covering five themes: (1) General prescription stipulations, (2) assessments prior to prescription, (3) care and treatment plan, (4) discontinuation, and (5) long-term treatment.

conclusionsIn this practice guideline, novel information was provided about detailed indication and thresholds of symptoms, risk factors, circumstances at which APs should be stopped or tapered, specific criteria for justifying long-term treatment, involvement of the multidisciplinary team, and family caregiver in the process of prescription. The practice guideline is based on formal consensus of clinicians and consumer experts and provides clinicians relevant practical information that is lacking in current guidelines.

Indexed as

AgedAntipsychotic AgentsConsensusDelphi TechniqueDementiaHomes for the AgedHumansNursing HomesPractice Guidelines as TopicAntipsychotic Agentsdementianursing homespsychopharmacology

Identifiers

PMID26062126
PMCPMC4582430

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.