Evidence map›Paper›PMID 26060820›Full record

Trial reportBioMed research international2015

The effect of nicotine dependence on psychopathology in patients with schizophrenia.

Anne Yee, Nik Nasyrah Bt Nek Mohamed, Aili Hanim Binti Hashim, Huai Seng Loh, Manveen Kaur Harbajan Singh, Chong Guan Ng, S T Jambunathan

Open access · hybridAbstract readClinical Trial
In one paragraph

Trial report in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Anne YeeDepartment of Psychological Medicine, Faculty of Medicine Building, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Nik Nasyrah Bt Nek MohamedDepartment of Psychiatry and Mental Health, Hospital Selayang, Lebuhraya Selayang-Kepong, 68100 Batu Caves, Selangor, Malaysia.
Aili Hanim Binti HashimDepartment of Psychological Medicine, Faculty of Medicine Building, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Huai Seng LohClinical Academic Unit (Family Medicine), Newcastle University Medicine Malaysia, No.1 Jalan Sarjana 1, Kota Ilmu, Educity@Iskandar, 79200 Nusajaya, Johor, Malaysia.ORCID 0000-0003-0904-0503
Manveen Kaur Harbajan SinghDepartment of Psychological Medicine, Faculty of Medicine Building, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Chong Guan NgDepartment of Psychological Medicine, Faculty of Medicine Building, University of Malaya, 50603 Kuala Lumpur, Malaysia.
S T JambunathanDepartment of Psychological Medicine, Faculty of Medicine Building, University of Malaya, 50603 Kuala Lumpur, Malaysia.
University of Malaya · MYHospital Selayang · MYNewcastle University Medicine Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOur study aims to determine the prevalence of nicotine dependence and investigate the effect of nicotine dependence on psychopathology among schizophrenia patients.

methodsA cross-sectional study was carried out in an outpatient psychiatric clinic at a general hospital in Malaysia. 180 recruited subjects were administered the Malay version of Mini International Neuropsychiatric Interview (MINI), the Positive and Negative Symptom Scale (PANSS), and the Malay version of Fagerstrom Test for Nicotine Dependence (FTND-M) questionnaires.

resultsThe prevalence of nicotine dependence among the subjects was 38.1% (n = 69) and they were mainly composed of male gender, Malay ethnicity, being treated with atypical antipsychotics, and taking other illicit drugs or alcohol. Subjects with severe nicotine dependence scored less in the negative subscale of PANSS compared with the nonsmokers (P = 0.011). On performing the hierarchy multiple regressions, dependence status still significantly predicted negative scores after adjusting the confounders (t = -2.87, P = 0.005).

conclusionThe rate of nicotine use disorder among schizophrenia patients in this study is higher than that of the general population in Malaysia. The significant association between nicotine dependence and negative psychopathology symptoms will help the healthcare practitioners in their management of nicotine dependence among schizophrenia patients.

Indexed as

SchizophreniaSchizophrenic PsychologyTobacco Use DisorderAdultAntipsychotic AgentsCross-Sectional StudiesFemaleHumansMalaysiaMaleMiddle AgedAntipsychotic Agents

Identifiers

PMID26060820
PMCPMC4427765
OpenAlexW2134685228

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.