Evidence map›Paper›PMID 26060816›Full record

Trial reportBioMed research international2015

Decreased pulmonary function in school children in Western Japan after exposures to Asian desert dusts and its association with interleukin-8.

Masanari Watanabe, Hisashi Noma, Jun Kurai, Hiroyuki Sano, Rumiko Saito, Satoshi Abe, Yutaka Kimura, Setsuya Aiba, Mitsuo Oshimura, Akira Yamasaki and 1 more

Open access · hybridAbstract readClinical TrialMulticenter Study
In one paragraph

Trial report in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Possible modulating functions of probioticFrontiers in cellular and infection microbiology · 2023
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Short-term effects of particle size fractions on lung function of late adolescents.Environmental science and pollution research international · 2018
    Article
  8. Review
  9. Estimation of the effects of heavy Asian dust on respiratory function by definition type.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2017
    Article
  10. Effects of Asian Dust Particles on the Early-Stage Antigen-Induced Immune Response of Asthma in NC/Nga Mice.International journal of environmental research and public health · 2016
    Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Masanari WatanabeDepartment of Respiratory Medicine and Rheumatology, Tottori University Hospital, Yonago 683-8504, Japan.
Hisashi NomaDepartment of Data Science, Institute of Statistical Mathematics, Tokyo 190-8562, Japan.ORCID 0000-0002-2520-9949
Jun KuraiDepartment of Respiratory Medicine and Rheumatology, Tottori University Hospital, Yonago 683-8504, Japan.
Hiroyuki SanoDepartment of Respiratory Medicine and Allergology, Kinki University Faculty of Medicine, Osakasayama 589-8511, Japan.
Rumiko SaitoDepartment of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Sendai 980-8574, Japan.
Satoshi AbeChromosome Engineering Research Center, Tottori University, Tottori 683-8504, Japan.ORCID 0000-0003-1153-0720
Yutaka KimuraChromosome Engineering Research Center, Tottori University, Tottori 683-8504, Japan.
Setsuya AibaChromosome Engineering Research Center, Tottori University, Tottori 683-8504, Japan.
Mitsuo OshimuraDepartment of Dermatology, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.
Akira YamasakiDepartment of Respiratory Medicine and Rheumatology, Tottori University Hospital, Yonago 683-8504, Japan.
Eiji ShimizuDepartment of Respiratory Medicine and Rheumatology, Tottori University Hospital, Yonago 683-8504, Japan.
Tottori University Hospital · JPTottori University · JPTohoku University · JPKindai University · JPThe Institute of Statistical Mathematics · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of the study was to investigate the influence of Asian dust storms (ADS) on pulmonary function of school children and the relationship of this effect with interleukin-8. Morning peak expiratory flow (PEF) was measured daily in 399 children from April to May 2012 and in 384 of these children from March to May 2013. The data were analyzed for an association between ADS events and PEF by linear mixed models. Interleukin-8 transcriptional activity was assessed in THP-G8 cells stimulated by airborne particles collected on ADS days. Seven ADS days were identified: April 23 and 24, 2012; March 8 to 10, 2013; and March 19 and 20, 2013. Changes in PEF after ADS exposure were -8.17 L/min (95% confidence interval, -11.40 to -4.93) in 2012 and -1.17 L/min (-4.07 to 1.74) in 2013, and there was a significant difference between 2012 and 2013. Interleukin-8 transcriptional activity was significantly higher in 2012 at 10.6 ± 2.9-fold compared to 3.7 ± 0.4 in March 8 to 10, 2013, and 2.3 ± 0.2 in March 19 and 20, 2013. The influence of ADS events on pulmonary function of children differs with each ADS event and may be related to interleukin-8 production.

Indexed as

Cyclonic StormsDustLungTranscription, GeneticAsian PeopleCell LineChildChild, PreschoolEnvironmental ExposureHumansInterleukin-8JapanMaleRespiratory Function TestsCXCL8 protein, humanDustInterleukin-8

Identifiers

PMID26060816
PMCPMC4427824
OpenAlexW2065740637

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.