Evidence map›Paper›PMID 26060726›Full record

ArticleIranian journal of public health2014

Sero-Prevalence of Antibodies against Varicella Zoster Virus in Children under Seven-Years Old in 2012 in Tehran, Iran.

Yasaman Vojgani, Saeed Zarei, Samira Rajaei, Leili Chamani-Tabriz, Fatemeh Ghaemimanesh, Nematallah Mohammadinia, Mahmood Jeddi-Tehrani

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Iranian journal of public health, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Varicella infection in the Middle East: Prevalence, complications, and vaccination.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Yasaman Vojgani1. Monoclonal Antibody Research Center, Avicenna Research Institute, ACECR , Tehran, Iran ; 2. Islamic, Azad University, Science and Research Branch , Arak, Iran.
Saeed Zarei1. Monoclonal Antibody Research Center, Avicenna Research Institute, ACECR , Tehran, Iran.
Samira Rajaei3. Lab Sciences Department, School of Allied Medicine, Tehran University of Medical Sciences (TUMS) , Tehran, Iran.
Leili Chamani-Tabriz4. Reproductive Biotechnology Research Center, Avicenna Research Institute, ACECR.
Fatemeh Ghaemimanesh1. Monoclonal Antibody Research Center, Avicenna Research Institute, ACECR , Tehran, Iran.
Nematallah Mohammadinia5. East Health Center, Shahid Beheshti University of Medical Science , Tehran, Iran.
Mahmood Jeddi-Tehrani1. Monoclonal Antibody Research Center, Avicenna Research Institute, ACECR , Tehran, Iran.
MAPNA Group (Iran) · IRBiotechnology Research Center · IRIslamic Azad University, Science and Research Branch · IRShahid Beheshti University of Medical Sciences · IRTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVaricella zoster virus (VZV) is a member of herpes family viruses, which causes varicella (chickenpox) after primary infection and herpes zoster (shingles) because of latent virus reactivation from dorsal root ganglia. Generally, prevalence of varicella antibodies increases with age. We aimed to compare the prevalence of anti-VZV antibody in children under seven years old, in order to obtain a preliminarily picture of general presence of these antibodies to design an immunization plan.

methodsIn this cross-sectional study, performed from September 2011 to September 2012 in Tehran, Iran, 267 serum samples including sera from 7 month old infants, n= 87; 18 month old children, n= 86; and 6 year old children, n= 94 were assessed for the presence of specific IgG antibodies against VZV, using ELISA technique.

results4.6% of 7 month, 12.8% of 18 month and 21.3% of 6-year-old children were seropositive. No relation was found between demographic variables (e.g. age and birth weight) and seropositivity in these age groups. VZV antibodies increased with age. Serum levels of varicella antibodies were elevated in 18 months old compared to 7 months old children, significantly (P < 0.001).

conclusionIn view of the significant elevation of VZV antibodies in children from 7 months to 18 months of age and rate of seronegative children, our results support the necessity of varicella immunization between 7 and 18 months of age in order to prevent viral infection.

Indexed as

AntibodyChildrenPrevalenceVaricella-zoster virus

Identifiers

PMID26060726
PMCPMC4449508
OpenAlexW2157412633

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.