Evidence map›Paper›PMID 26060476›Full record

ArticleAfrican health sciences2014

Evaluation of haematological, hepatic and renal functions of petroleum tanker drivers in Lagos, Nigeria.

Olufunsho Awodele, Ademola A Sulayman, Alade Akintonwa

Abstract read
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Article in African health sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Olufunsho AwodeleDepartment of Pharmacology, Therapeutics & Toxicology, College of Medicine, University of Lagos, PMB 12003, Lagos-Nigeria.
Ademola A SulaymanDepartment of Pharmacology, Therapeutics & Toxicology, College of Medicine, University of Lagos, PMB 12003, Lagos-Nigeria.
Alade AkintonwaDepartment of Pharmacology, Therapeutics & Toxicology, College of Medicine, University of Lagos, PMB 12003, Lagos-Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHydrocarbons which are among the major components of petroleum products are considered toxic and have been implicated in a number of human diseases. Tanker drivers are continuously exposed to hydrocarbons by inhalation and most of these drivers do not use protective devices to prevent inhalation of petroleum products; nor do they visit hospital regularly for routine check-up.

objectiveIn view of this occupational hazard, we investigated the haematological, renal and hepatic functions of workers of petroleum tankers drivers in Lagos, Nigeria.

methodTwenty-five tanker drivers' and fifteen control subjects were randomly selected based on the selection criteria of not smoking and working for minimum of 5 years as petroleum tanker driver. The liver, renal and haematological parameters were analyzed using automated clinical and haematological analyzers while the lipid peroxidation and antioxidant level tests were assayed using standard methods.

resultsThere were significant (p ≤ 0.05) increases in the levels of serum alanine amino transferase (31.14±13.72; 22.38±9.89), albumin (42.50±4.69; 45.36±1.74) and alkaline phosphatase (84.04±21.89; 62.04±23.33) of petroleum tanker drivers compared with the controls. A significant (p≤0.05) increase in the levels of creatinine, urea and white blood cells of the tanker drivers, compared with the controls, were also obtained.

conclusionThe results have enormous health implications of continuous exposure to petroleum products reflected hepatic and renal damage of petroleum tanker drivers. Therefore, there is need for this group of workers to be sensitized on the importance of protective devises, regular medical checkup and management.

Indexed as

Automobile DrivingAdultBlood Chemical AnalysisBlood SedimentationCase-Control StudiesHealth StatusHematologic TestsHumansHydrocarbonsInhalation ExposureKidney Function TestsLiver Function TestsMiddle AgedNigeriaOccupational ExposurePetroleumHydrocarbonsPetroleumhydrocarbonsliver functionsoxidative stresspetroleum tanker driversrenal

Identifiers

PMID26060476
PMCPMC4449049

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.