Evidence map›Paper›PMID 26060464›Full record

ArticleAfrican health sciences2014

A new diagnostic marker for acute pulmonary embolism in emergency department: mean platelet volume.

Fahrettin Talay, Tarık Ocak, Aytekin Alcelik, Kurşat Erkuran, Akcan Akkaya, Arif Duran, Abdullah Demirhan, Ozlem Kar Kurt, Zehra Asuk

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in African health sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07023705 (Monocyte To Large Platelet Ratio As A Diagnostic Marker For Acute Pulmonary Embolism), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07023705 completednot on this mapstarted 2024, after this paper: background citation

Monocyte To Large Platelet Ratio As A Diagnostic Marker For Acute Pulmonary Embolism

TypeobservationalSponsorAin Shams UniversityRan2024 to 2025Enrolled53ConditionsPulmonary Embolism (Diagnosis), DiagnosisArmsMonocyte to Large Platelet Ratio (MLPR)
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Diagnostic Role of Mean-Platelet Volume in Acute Pulmonary Embolism: A Meta-analysis and Systematic Review.Clinical medicine insights. Circulatory, respiratory and pulmonary medicine · 2020
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Fahrettin TalayDepartment of Chest Diseases, Abant Izzet Baysal Medical Faculty, Bolu, Turkey.
Tarık OcakDepartment of Emergency Medicine, Abant Izzet Baysal Medical Faculty, Bolu, Turkey.
Aytekin AlcelikDepartment of Internal Medicine, Abant Izzet Baysal Medical Faculty, Bolu, Turkey.
Kurşat ErkuranDepartment of Emergency Medicine, Abant Izzet Baysal Medical Faculty, Bolu, Turkey.
Akcan AkkayaDepartment of Anesthesiology and Reanimation, Abant Izzet Baysal Medical Faculty, Bolu, Turkey.
Arif DuranDepartment of Emergency Medicine, Abant Izzet Baysal Medical Faculty, Bolu, Turkey.
Abdullah DemirhanDepartment of Anesthesiology and Reanimation, Abant Izzet Baysal Medical Faculty, Bolu, Turkey.
Ozlem Kar KurtDepartment of Chest Diseases, Abant Izzet Baysal Medical Faculty, Bolu, Turkey.
Zehra AsukDepartment of Chest Diseases, Abant Izzet Baysal Medical Faculty, Bolu, Turkey.
Bolu Abant İzzet Baysal University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the diagnostic importance of mean platelet volume (MPV) on acute pulmonary embolism (APE) in the emergency Department (ED).

methodsSubjects were selected from patients admitted to ED with clinically suspected APE. Demographic, anthropometric and serologic data were collected for each patient.

resultsA total of 315 consecutive patients were analyzed, including 150 patients (53.44 ± 15.14 y; 92 men/58 women) in APE group and 165 patients (49.80 ±13.76y; 94 men/71 women) in the control group. MPV in the APE group was significantly higher than in the control group (9.42±1.22 fl vs. 8.04±0.89 fl, p<0.0001). The best cut-off values for MPV when predicting APE in patients with clinically suspected APE presenting at the ED were 8.55 fl (sensitivity 82.2%; specificity 52.3%).

conclusionsMPV is a helpful parameter for the diagnosis of APE in ED, for the first time in the literature.

Indexed as

Acute DiseaseAdultAgedBiomarkersBlood PlateletsCross-Sectional StudiesEmergency Medical ServicesFemaleHumansMaleMean Platelet VolumeMiddle AgedPulmonary EmbolismRetrospective StudiesRisk FactorsROC CurveBiomarkersAcute pulmonary embolismemergency departmentmean platelet volumethrombus

Identifiers

PMID26060464
PMCPMC4449081
OpenAlexW2089387638

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.