Evidence map›Paper›PMID 26060410›Full record

ArticleOncoTargets and therapy2015

Percutaneous microwave ablation combined with simultaneous transarterial chemoembolization for the treatment of advanced intrahepatic cholangiocarcinoma.

Guo-Wei Yang, Qing Zhao, Sheng Qian, Liang Zhu, Xu-Dong Qu, Wei Zhang, Zhi-Ping Yan, Jie-Min Cheng, Qing-Xin Liu, Rong Liu and 1 more

Abstract read
In one paragraph

Article in OncoTargets and therapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Radiological Loco-Regional Treatments for Cholangiocarcinoma: A Systematic Review of the Literature.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Ablation of Intrahepatic Cholangiocarcinoma.Seminars in interventional radiology · 2019
    Review
  12. Article
  13. Ablative therapies for intrahepatic cholangiocarcinoma.Hepatobiliary surgery and nutrition · 2018
    Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Guo-Wei YangDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Qing ZhaoDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Sheng QianDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Liang ZhuDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Xu-Dong QuDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Wei ZhangDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Zhi-Ping YanDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Jie-Min ChengDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Qing-Xin LiuDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Rong LiuDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Jian-Hua WangDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo retrospectively evaluate the safety and efficacy of ultrasound-guided percutaneous microwave ablation (MWA) combined with simultaneous transarterial chemoembolization (TACE) in the treatment of patients with advanced intrahepatic cholangiocarcinoma (ICC).

methodsAll patients treated with ultrasound-guided percutaneous MWA combined with simultaneous TACE for advanced ICC at our institution were included. Posttreatment contrast-enhanced computed tomography and/or magnetic resonance imaging were retrieved and reviewed for tumor response to the treatment. Routine laboratory studies, including hematology and liver function tests were collected and analyzed. Procedure-related complications were reviewed and survival rates were analyzed.

resultsFrom January 2011 to December 2014, a total of 26 advanced ICC patients were treated at our single institute with ultrasound-guided percutaneous MWA combined with simultaneous TACE. There were 15 males and eleven females with an average age of 57.9±10.4 years (range, 43-75 years). Of 26 patients, 20 (76.9%) patients were newly diagnosed advanced ICC without any treatment, and six (23.1%) were recurrent and treated with surgical resection of the original tumor. The complete ablation rate was 92.3% (36/39 lesions) for advanced ICC. There were no major complications observed. There was no death directly from the treatment. Median progression-free survival and overall survival were 6.2 and 19.5 months, respectively. The 6-, 12-, and 24-month survival rates were 88.5%, 69.2%, and 61.5%, respectively.

conclusionThe study suggests that ultrasound-guided percutaneous MWA combined with simultaneous TACE therapy can be performed safely in all patients with advanced ICC. The complete ablation rate was high and there was no major complication. The overall 24-month survival was 61.5%.

Indexed as

interventional radiologyintrahepatic cholangiocarcinomamicrowave ablationtransarterial chemoembolization

Identifiers

PMID26060410
PMCPMC4454214

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.