ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2015
Mortality Associated With Seasonal and Pandemic Influenza Among Pregnant and Nonpregnant Women of Childbearing Age in a High-HIV-Prevalence Setting-South Africa, 1999-2009.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Influenza Vaccine Efficacy and Effectiveness in Pregnant Women: Systematic Review and Meta-analysis.Maternal and child health journal · 2020Pooled it
- Incidence of influenza virus infection among pregnant women: a systematic review.BMC pregnancy and childbirth · 2017Pooled it
- Changes in the Epidemiology of Influenza and Respiratory Syncytial Virus During 2020-2022 Relative to the Pre-COVID-19 Pandemic Period (2017-2020) From Systematic Sentinel Syndromic Surveillance in South Africa.Influenza and other respiratory viruses · 2026Article
- The burden of influenza among Kenyan pregnant and postpartum women and their infants, 2015-2020.Influenza and other respiratory viruses · 2022Article
- COVID-19, Influenza and RSV: Surveillance-informed prevention and treatment - Meeting report from an isirv-WHO virtual conference.Antiviral research · 2022Article
- An evaluation of an influenza vaccination campaign targeting pregnant women in 27 clinics in two provinces of South Africa, 2015 - 2018.BMC health services research · 2021Article
- Vaccination of pregnant women against influenza: what is the optimal timing?Human vaccines & immunotherapeutics · 2021Article
- A Retrospective observational cohort study of the effect of antenatal influenza vaccination on birth outcomes in Cape Town, South Africa, 2015-2016.Influenza and other respiratory viruses · 2021Observational
- Estimated impact of maternal vaccination on global paediatric influenza-related in-hospital mortality: A retrospective case series.EClinicalMedicine · 2021Article
- Epidemiology of 631 Cases of COVID-19 Identified in Jiangsu Province Between January 1st and March 20th 2020: Factors Associated with Disease Severity and Analysis of Zero Mortality.Medical science monitor : international medical journal of experimental and clinical research · 2021Article
- Influenza disease burden among potential target risk groups for immunization in South Africa, 2013-2015.Vaccine · 2020Article
- Optimal Profile Limits for Maternal Mortality Rates (MMR) Influenced by Haemorrhage and Unsafe Abortion in South Sudan.Journal of pregnancy · 2020Article
- Article
- The Impact of Influenza and Tuberculosis Interaction on Mortality Among Individuals Aged ≥15 Years Hospitalized With Severe Respiratory Illness in South Africa, 2010-2016.Open forum infectious diseases · 2019Article
- Prioritization of risk groups for influenza vaccination in resource limited settings - A case study from South Africa.Vaccine · 2019Article
- Burden, effectiveness and safety of influenza vaccines in elderly, paediatric and pregnant populations.Therapeutic advances in vaccines and immunotherapy · 2019Review
- Uptake and cost of influenza vaccines in a private health insured South African population.Southern African journal of infectious diseases · 2018Article
- Critically ill healthcare workers with the middle east respiratory syndrome (MERS): A multicenter study.PloS one · 2018Article
- Influenza epidemiology and immunization during pregnancy: Final report of a World Health Organization working group.Vaccine · 2017Article
- Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundInformation on the mortality burden associated with seasonal and pandemic influenza virus infection among pregnant women is scarce in most settings, particularly in sub-Saharan Africa where pregnancy and maternal mortality rates as well as human immunodeficiency virus (HIV) prevalence are elevated.
methodsWe used an ecological study design to estimate the seasonal and A(H1N1)pdm09 influenza-associated mortality among pregnant and nonpregnant women of childbearing age (15-49 years) by HIV serostatus during 1999-2009 in South Africa. Mortality rates were expressed per 100 000 person-years.
resultsDuring 1999-2009, the estimated mean annual seasonal influenza-associated mortality rates were 12.6 (123 deaths) and 7.3 (914 deaths) among pregnant and nonpregnant women, respectively. Among pregnant women, the estimated mean annual seasonal influenza-associated mortality rates were 74.9 (109 deaths) among HIV-infected and 1.5 (14 deaths) among HIV-uninfected individuals. Among nonpregnant women, the estimated mean annual seasonal influenza-associated mortality rate was 41.2 (824 deaths) among HIV-infected and 0.9 (90 deaths) among HIV-uninfected individuals. Pregnant women experienced an increased risk of seasonal influenza-associated mortality compared with nonpregnant women (relative risk [RR], 2.8; 95% confidence interval [CI], 1.7-3.9). In 2009, the estimated influenza A(H1N1)pdm09-associated mortality rates were 19.3 (181 deaths) and 9.4 (1189 deaths) among pregnant and nonpregnant women, respectively (RR, 3.2; 95% CI, 2.3-4.1).
conclusionsAmong women of childbearing age, the majority of estimated seasonal influenza-associated deaths occurred in HIV-infected individuals. Pregnant women experienced an increased risk of death associated with seasonal and A(H1N1)pdm09 influenza infection compared with nonpregnant women.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.