Evidence map›Paper›PMID 26060028›Full record

ReviewBest practice & research. Clinical anaesthesiology2015

Pulmonary complications of cardiopulmonary bypass.

Julie L Huffmyer, Danja S Groves

Registry-linked trialOpen access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Best practice & research. Clinical anaesthesiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04760340 (TELUS in Cardiac Surgery Patients. Effect of CPB and Relation to Postoperative Events), which is not on this map. Cited by 71 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 3 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04760340 unknown statusnot on this mapstarted 2021, after this paper: background citation

TELUS in Cardiac Surgery Patients. Effect of CPB and Relation to Postoperative Events (PORE).

Typeobservational_patient_registrySponsorClinique du MillenaireRan2021 to 2021Enrolled120ConditionsCardiac Surgical Procedures
3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 3 syntheses or guidelines pooled it, 136 citations in OpenAlex.

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  15. Changes in mucin expression in the lungs of infant piglets following cardiopulmonary bypass with deep hypothermic circulatory arrest.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2026
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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Julie L HuffmyerDepartment of Anesthesiology, University of Virginia, PO Box 800710, Charlottesville, VA 22908-0710, USA. Electronic address: jh3wd@virginia.edu.
Danja S GrovesDepartment of Anesthesiology, University of Virginia, PO Box 800710, Charlottesville, VA 22908-0710, USA. Electronic address: dgroves@virginia.edu.
University of Virginia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary complications after the use of extracorporeal circulation are common, and they range from transient hypoxemia with altered gas exchange to acute respiratory distress syndrome (ARDS), with variable severity. Similar to other end-organ dysfunction after cardiac surgery with extracorporeal circulation, pulmonary complications are attributed to the inflammatory response, ischemia-reperfusion injury, and reactive oxygen species liberated as a result of cardiopulmonary bypass. Several factors common in cardiac surgery with extracorporeal circulation may worsen the risk of pulmonary complications including atelectasis, transfusion requirement, older age, heart failure, emergency surgery, and prolonged duration of bypass. There is no magic bullet to prevent or treat pulmonary complications, but supportive care with protective ventilation is important. Targets for the prevention of pulmonary complications include mechanical, surgical, and anesthetic interventions that aim to reduce the contact activation, systemic inflammatory response, leukocyte sequestration, and hemodilution associated with extracorporeal circulation.

Indexed as

AnimalsCardiopulmonary BypassExtracorporeal CirculationHumansLung DiseasesPostoperative ComplicationsRespiratory Distress Syndromeacute lung injuryacute respiratory distress syndromecardiopulmonary bypassextracorporeal circulationpulmonary complications

Identifiers

PMID26060028
PMCPMC10068650
OpenAlexW2109324622

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.