ArticleScientific reports2015
Intracellular microRNA profiles form in the Xenopus laevis oocyte that may contribute to asymmetric cell division.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 8 citations in OpenAlex.
- Single Cell Proteomics by Data-Independent Acquisition To Study Embryonic Asymmetry inAnalytical chemistry · 2019Article
- Asymmetric distribution of biomolecules of maternal origin in the Xenopus laevis egg and their impact on the developmental plan.Scientific reports · 2018Article
- Identification and characterization of Xenopus tropicalis common progenitors of Sertoli and peritubular myoid cell lineages.Biology open · 2016Article
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5 authors at 4 institutions in 4 countries.
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Abstract
Asymmetric distribution of fate determinants within cells is an essential biological strategy to prepare them for asymmetric division. In this work we measure the intracellular distribution of 12 maternal microRNAs (miRNA) along the animal-vegetal axis of the Xenopus laevis oocyte using qPCR tomography. We find the miRNAs have distinct intracellular profiles that resemble two out of the three profiles we previously observed for mRNAs. Our results suggest that miRNAs in addition to proteins and mRNAs may have asymmetric distribution within the oocyte and may contribute to asymmetric cell division as cell fate determinants.
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