Evidence map›Paper›PMID 26059788›Full record

ReviewHNO2015

[Personalized medicine in otology. The role of genetic diagnostics in patients with hearing impairment].

N Friese, K Braun, M Müller, A Tropitzsch

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in HNO, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

N FrieseKlinik für Hals-, Nasen- und Ohrenheilkunde, Universitätsklinikum Tübingen, Elfriede-Aulhorn-Straße 5, 72076, Tübingen, Deutschland.
K Braun
M Müller
A Tropitzsch
Universitätsklinikum Tübingen · DECarl von Ossietzky Universität Oldenburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundClassification of diseases on the molecular level is the basis for personalized medicine. Personalized medicine proposes to improve efficiency and quality of care, to reduce side effects and to increase long-term cost-effectiveness.

objectivesThis paper is concerned with the role of genetic diagnostics in patients with a cochlear implant. MATERIAL AND

methodsA selective literature search in PubMed was performed.

resultsGenetic diagnosis allows ruling out syndromic hearing loss and thus prevents follow-up studies. It allows genetic counseling, prognosis and advice on family planning and targeted prevention. Due to its minimal invasiveness, it is suitable for evaluation of factors accounting for hearing loss in children.

conclusionsMolecular medicine plays a major role in the treatment of sensorineural hearings loss with cochlear implants.

Indexed as

Cochlear ImplantsGenetic CounselingGenetic Predisposition to DiseaseGenetic TestingHearing Loss, SensorineuralHumansOtolaryngologyPrecision Medicine

Identifiers

PMID26059788
OpenAlexW631810466

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.