Evidence map›Paper›PMID 26059023›Full record

ArticleScientific reports2015

Electronic polymers in lipid membranes.

Patrik K Johansson, David Jullesson, Anders Elfwing, Sara I Liin, Chiara Musumeci, Erica Zeglio, Fredrik Elinder, Niclas Solin, Olle Inganäs

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Patrik K Johansson1] Biomolecular and Organic Electronics, Department of Physics Chemistry and Biology, Linköping University, SE-58183, Linköping, Sweden [2] Current address: National ESCA Surface Analysis Center for Biomedical Problems, Department of Bioengineering, University of Washington, Seattle, WA, US-98195, United States.
David Jullesson1] Biomolecular and Organic Electronics, Department of Physics Chemistry and Biology, Linköping University, SE-58183, Linköping, Sweden [2] Current address: Systems and Synthetic Biology, Department of Chemical and Biological Engineering, Chalmers University of Technology, SE-41296, Gothenburg, Sweden.
Anders ElfwingBiomolecular and Organic Electronics, Department of Physics Chemistry and Biology, Linköping University, SE-58183, Linköping, Sweden.
Sara I LiinDepartment of Clinical and Experimental Medicine, Linköping University, SE-58185, Linköping, Sweden.
Chiara MusumeciBiomolecular and Organic Electronics, Department of Physics Chemistry and Biology, Linköping University, SE-58183, Linköping, Sweden.
Erica ZeglioBiomolecular and Organic Electronics, Department of Physics Chemistry and Biology, Linköping University, SE-58183, Linköping, Sweden.
Fredrik ElinderDepartment of Clinical and Experimental Medicine, Linköping University, SE-58185, Linköping, Sweden.
Niclas SolinBiomolecular and Organic Electronics, Department of Physics Chemistry and Biology, Linköping University, SE-58183, Linköping, Sweden.
Olle InganäsBiomolecular and Organic Electronics, Department of Physics Chemistry and Biology, Linköping University, SE-58183, Linköping, Sweden.
Linköping University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electrical interfaces between biological cells and man-made electrical devices exist in many forms, but it remains a challenge to bridge the different mechanical and chemical environments of electronic conductors (metals, semiconductors) and biosystems. Here we demonstrate soft electrical interfaces, by integrating the metallic polymer PEDOT-S into lipid membranes. By preparing complexes between alkyl-ammonium salts and PEDOT-S we were able to integrate PEDOT-S into both liposomes and in lipid bilayers on solid surfaces. This is a step towards efficient electronic conduction within lipid membranes. We also demonstrate that the PEDOT-S@alkyl-ammonium:lipid hybrid structures created in this work affect ion channels in the membrane of Xenopus oocytes, which shows the possibility to access and control cell membrane structures with conductive polyelectrolytes.

Indexed as

ElectronsMembranes, ArtificialLipid BilayersLipidsMicroscopy, Atomic ForcePolymersLipid BilayersLipidsMembranes, ArtificialPolymers

Identifiers

PMID26059023
PMCPMC4462020
OpenAlexW1885666282

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.