ArticleHuman brain mapping2015
Comparison of diffusion tractography and tract-tracing measures of connectivity strength in rhesus macaque connectome.
Article in Human brain mapping, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
77 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review on the quantitative relationship between structural and functional network connectivity strength in mammalian brains.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019Pooled it
- Macroscopic resting state model predicts theta burst stimulation response: A randomized trial.PLoS computational biology · 2023Trial
- Structural neural markers of response to cognitive behavioral therapy in pediatric obsessive-compulsive disorder.Journal of child psychology and psychiatry, and allied disciplines · 2020Trial
- Predicting Surgery Targets in Temporal Lobe Epilepsy through Structural Connectome Based Simulations.PLoS computational biology · 2015Trial
- Conserved fiber topography of the anterior limb of the internal capsule in treatment-resistant psychiatric patients.bioRxiv : the preprint server for biology · 2026Article
- An anatomical and connectivity atlas of the tree shrew brain to bridge rodent and primate neuroanatomy.PLoS biology · 2026Article
- Reconstructing the human brain's wiring diagram from axons up.Trends in neurosciences · 2026Review
- Reduced brain structural similarity is associated with maturation, neurobiological features, and clinical status in schizophrenia.Nature communications · 2025Article
- Considerations and recommendations from the ISMRM diffusion study group for preclinical diffusion MRI: Part 1: In vivo small-animal imaging.Magnetic resonance in medicine · 2025Review
- The spatial extent of anatomical connections within the thalamus varies across the cortical hierarchy in humans and macaques.bioRxiv : the preprint server for biology · 2025Article
- A map of white matter tracts in a lesser ape, the lar gibbon.Brain structure & function · 2024Article
- Human Claustrum Connections: Robust In Vivo Detection by DWI-Based Tractography in Two Large Samples.Human brain mapping · 2024Article
- Age Trajectories of the Structural Connectome in Child and Adolescent Offspring of Individuals With Bipolar Disorder or Schizophrenia.Biological psychiatry global open science · 2024Article
- Tractography passes the test: Results from the diffusion-simulated connectivity (disco) challenge.NeuroImage · 2023Article
- Assortative mixing in micro-architecturally annotated brain connectomes.Nature communications · 2023Article
- Identifying subcortical connectivity during brain tumor surgery: a multimodal study.Brain structure & function · 2023Article
- Insights from the IronTract challenge: Optimal methods for mapping brain pathways from multi-shell diffusion MRI.NeuroImage · 2022Article
- Review
- Article
- Comparing human and chimpanzee temporal lobe neuroanatomy reveals modifications to human language hubs beyond the frontotemporal arcuate fasciculus.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
17 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
With the mapping of macroscale connectomes by means of in vivo diffusion-weighted MR Imaging (DWI) rapidly gaining in popularity, one of the necessary steps is the examination of metrics of connectivity strength derived from these reconstructions. In the field of human macroconnectomics the number of reconstructed fiber streamlines (NOS) is more and more used as a metric of cortico-cortical interareal connectivity strength, but the link between DWI NOS and in vivo animal tract-tracing measurements of anatomical connectivity strength remains poorly understood. In this technical report, we communicate on a comparison between DWI derived metrics and tract-tracing metrics of projection strength. Tract-tracing information on projection strength of interareal pathways was extracted from two commonly used macaque connectome datasets, including (1) the CoCoMac database of collated tract-tracing experiments of the macaque brain and (2) the high-resolution tract-tracing dataset of Markov and Kennedy and coworkers. NOS and density of reconstructed fiber pathways derived from DWI data acquired across 10 rhesus macaques was found to positively correlate to tract-tracing based measurements of connectivity strength across both the CoCoMac and Markov dataset (both P < 0.001), suggesting DWI NOS to form a valid method of assessment of the projection strength of white matter pathways. Our findings provide confidence of in vivo DWI connectome reconstructions to represent fairly realistic estimates of the wiring strength of white matter projections. Our cross-modal comparison supports the notion of in vivo DWI to be a valid methodology for robust description and interpretation of brain wiring.
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