ArticleMarine drugs2015
Effect of Marine Collagen Peptides on Physiological and Neurobehavioral Development of Male Rats with Perinatal Asphyxia.
Article in Marine drugs, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 41 citations in OpenAlex.
- Effects of Composite Supplement Containing Collagen Peptide and Ornithine on Skin Conditions and Plasma IGF-1 Levels-A Randomized, Double-Blind, Placebo-Controlled Trial.Marine drugs · 2018Trial
- Effectiveness of Essence of Chicken on Cognitive Function Improvement: A Randomized Controlled Clinical Trial.Nutrients · 2018Trial
- Bioactive Collagen Peptides in Veterinary and Biomedical Science-Part II: The Gut-Collagen Peptide Axis, Bile Acid Signaling, and Translational Therapeutic Applications.Veterinary sciences · 2026Review
- Marine-derived PUFAs and peptides for aging-related memory deficits: processing methods, pharmacokinetics, mechanistic insights, and clinical application.Frontiers in nutrition · 2026Review
- From Molecules to Mind: The Critical Role of Chitosan, Collagen, Alginate, and Other Biopolymers in Neuroprotection and Neurodegeneration.Molecules (Basel, Switzerland) · 2025Review
- Hydrolyzed Marine Collagen: Emerging Evidence of Benefits via the Oral Route - Review and Insights for Medical Aesthetics Practitioners.Clinical, cosmetic and investigational dermatology · 2025Review
- Marine Antioxidants from Marine Collagen and Collagen Peptides with Nutraceuticals Applications: A Review.Antioxidants (Basel, Switzerland) · 2024Review
- Potential Active Marine Peptides as Anti-Aging Drugs or Drug Candidates.Marine drugs · 2023Review
- Recovery of Bioactive Compounds from Marine Organisms: Focus on the Future Perspectives for Pharmacological, Biomedical and Regenerative Medicine Applications of Marine Collagen.Molecules (Basel, Switzerland) · 2023Review
- Isolation and Characterization of Collagen and Collagen Peptides with Hyaluronidase Inhibition Activity Derived from the Skin of Marlin (Molecules (Basel, Switzerland) · 2023Article
- Fish Waste: From Problem to Valuable Resource.Marine drugs · 2021Review
- Marine Collagen Hydrolysates Downregulate the Synthesis of Pro-Catabolic and Pro-Inflammatory Markers of Osteoarthritis and Favor Collagen Production and Metabolic Activity in Equine Articular Chondrocyte Organoids.International journal of molecular sciences · 2021Article
- Marine-Derived Collagen as Biomaterials for Human Health.Frontiers in nutrition · 2021Review
- Marine Collagen from Alternative and Sustainable Sources: Extraction, Processing and Applications.Marine drugs · 2020Review
- Bioaccessibility of Shore MagicHeliyon · 2018Article
- Marine Collagen Peptides from the Skin of Nile Tilapia (Oreochromis niloticus): Characterization and Wound Healing Evaluation.Marine drugs · 2017Article
- Fish Scale Collagen Peptides Protect against CoClOxidative medicine and cellular longevity · 2017Article
- Brain caspase-3 and intestinal FABP responses in preterm and term rats submitted to birth asphyxia.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2016Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Asphyxia during delivery produces long-term deficits in brain development. We investigated the neuroprotective effects of marine collagen peptides (MCPs), isolated from Chum Salmon skin by enzymatic hydrolysis, on male rats with perinatal asphyxia (PA). PA was performed by immersing rat fetuses with uterine horns removed from ready-to-deliver rats into a water bath for 15 min. Caesarean-delivered pups were used as controls. PA rats were intragastrically administered with 0.33 g/kg, 1.0 g/kg and 3.0 g/kg body weight MCPs from postnatal day 0 (PND 0) till the age of 90-days. Behavioral tests were carried out at PND21, PND 28 and PND 90. The results indicated that MCPs facilitated early body weight gain of the PA pups, however had little effects on early physiological development. Behavioral tests revealed that MCPs facilitated long-term learning and memory of the pups with PA through reducing oxidative damage and acetylcholinesterase (AChE) activity in the brain, and increasing hippocampus phosphorylated cAMP-response element binding protein (p-CREB) and brain derived neurotrophic factor (BDNF) expression.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.