Evidence map›Paper›PMID 26057747›Full record

ReviewInternational journal of molecular sciences2015

Cultivation, Genetic, Ethnopharmacology, Phytochemistry and Pharmacology of Moringa oleifera Leaves: An Overview.

Alessandro Leone, Alberto Spada, Alberto Battezzati, Alberto Schiraldi, Junior Aristil, Simona Bertoli

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 184 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
184citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

184 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Effects ofNutrients · 2025
    Pooled it
  2. Effect ofFrontiers in pharmacology · 2025
    Pooled it
  3. Molecules (Basel, Switzerland) · 2021
    Pooled it
  4. Potential ofNutrients · 2020
    Pooled it
  5. Impact of MaternalNutrients · 2024
    Trial
  6. Investigating the Impact ofJPGN reports · 2022
    Trial
  7. Effects ofNutrients · 2022
    Trial
  8. Nutrients · 2021
    Trial
  9. Effect ofNutrients · 2018
    Trial
  10. Article
  11. Article
  12. Tryptophan-RichMolecules (Basel, Switzerland) · 2026
    Article
  13. Enhanced cytotoxic activity ofNanoscale advances · 2026
    Article
  14. Effect ofOpen veterinary journal · 2026
    Article
  15. Review
  16. A bibliometric analysis ofOpen life sciences · 2026
    Article
  17. Biodiversity and genetic improvement ofFrontiers in plant science · 2026
    Review
  18. Article
  19. Article
  20. Impact of DietaryVeterinary sciences · 2025
    Article

124 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alessandro LeoneInternational Center for the Assessment of Nutritional Status (ICANS), University of Milan, Via Sandro Botticelli 21, 20133 Milan, Italy. alessandro.leone1@unimi.it.
Alberto SpadaDepartment of Agricultural and Environmental Sciences-Production, Landscape, Agroenergy (DISAA), University of Milan, Via Celoria 2, 20133 Milan, Italy. alberto.spada@unimi.it.
Alberto BattezzatiInternational Center for the Assessment of Nutritional Status (ICANS), University of Milan, Via Sandro Botticelli 21, 20133 Milan, Italy. alberto.battezzati@unimi.it.
Alberto SchiraldiDepartment of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Via Mangiagalli 25, 20133 Milan, Italy. alberto.schiraldi@unimi.it.
Junior AristilDepartment of Agricultural and Environmental Sciences-Production, Landscape, Agroenergy (DISAA), University of Milan, Via Celoria 2, 20133 Milan, Italy. junior.aristil@unimi.it.
Simona BertoliInternational Center for the Assessment of Nutritional Status (ICANS), University of Milan, Via Sandro Botticelli 21, 20133 Milan, Italy. simona.bertoli@unimi.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Moringa oleifera is an interesting plant for its use in bioactive compounds. In this manuscript, we review studies concerning the cultivation and production of moringa along with genetic diversity among different accessions and populations. Different methods of propagation, establishment and cultivation are discussed. Moringa oleifera shows diversity in many characters and extensive morphological variability, which may provide a resource for its improvement. Great genetic variability is present in the natural and cultivated accessions, but no collection of cultivated and wild accessions currently exists. A germplasm bank encompassing the genetic variability present in Moringa is needed to perform breeding programmes and develop elite varieties adapted to local conditions. Alimentary and medicinal uses of moringa are reviewed, alongside the production of biodiesel. Finally, being that the leaves are the most used part of the plant, their contents in terms of bioactive compounds and their pharmacological properties are discussed. Many studies conducted on cell lines and animals seem concordant in their support for these properties. However, there are still too few studies on humans to recommend Moringa leaves as medication in the prevention or treatment of diseases. Therefore, further studies on humans are recommended.

Indexed as

AntioxidantsHypoglycemic AgentsMoringa oleiferaPhenolsPlant ExtractsPlant LeavesPlant Physiological PhenomenaVitaminsAntioxidantsHypoglycemic AgentsPhenolsPlant ExtractsVitaminsbreedingcancerdiabetesdislipidemiaethnopharmacologygenetic variabilitymolecular markersMoringa oleiferapharmacologyphytochemistry

Identifiers

PMID26057747
PMCPMC4490473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.