Evidence map›Paper›PMID 26057686›Full record

ArticleThe Permanente journal2015

"Getting off the Bus Closer to Your Destination": Patients' Views about Pharmacogenetic Testing.

Susan Brown Trinidad, Tara B Coffin, Stephanie M Fullerton, James Ralston, Gail P Jarvik, Eric B Larson

Abstract read
In one paragraph

Article in The Permanente journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Susan Brown TrinidadResearch Scientist in Bioethics and Humanities at the University of Washington in Seattle. sbtrini@uw.edu.
Tara B CoffinDoctoral Candidate in the Institute for Public Health Genetics at the University of Washington in Seattle. tarabethanne@gmail.com.
Stephanie M FullertonAssociate Professor in Bioethics and Humanities at the University of Washington in Seattle. smfllrtn@uw.edu.
James RalstonAssociate Investigator at the Group Health Research Institute in Seattle, WA. ralston.j@ghc.org.
Gail P JarvikProfessor and Head of the Division of Medical Genetics at the University of Washington in Seattle. pair@uw.edu.
Eric B LarsonExecutive Director and Senior Investigator at the Group Health Research Institute in Seattle, WA. larson.e@ghc.org.

Funding

Genetic Discovery and Application in a Clinical Setting Continuing a PartnershipU01HG006375 · NHGRI · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI JARVIK, GAIL PAIRITZ, LARSON, ERIC B · 2011 to 2014
$4.1M
NHGRI NIH HHS 1U01HG006375-01NHGRI NIH HHS U01 HG006375
6 · The paper itself

Abstract

The authors conducted focus groups with patients prescribed antidepressants (pilot session plus 2 focus groups, n = 27); patients prescribed carbamazepine (2 focus groups, n = 17); and healthy patients (2 focus groups, n = 17). Although participants understood the potential advantages of pharmacogenetic testing, many felt that the risks (discrimination, stigmatization, physician overreliance on genomic results, and denial of certain medications) may outweigh the benefits. These concerns were shared across groups but were more strongly expressed among participants with chronic mental health diagnoses.

Indexed as

Patient Acceptance of Health CarePharmacogeneticsAdultAntidepressive AgentsFemaleFocus GroupsHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedPatient SatisfactionPhysician-Patient RelationsQualitative ResearchQuality of Health CareSocial StigmaAntidepressive Agents

Identifiers

PMID26057686
PMCPMC4500477

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.