Evidence map›Paper›PMID 26057600›Full record

ArticleJournal of colloid and interface science2015

Influence of binary microgel phase behavior on the assembly of multi-functional raspberry-structured microgel heteroaggregates.

Shalini Saxena, L Andrew Lyon

Abstract read
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In one paragraph

Article in Journal of colloid and interface science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shalini SaxenaSchool of Materials Science and Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA; Petit Institute for Biosciences and Bioengineering, Georgia Institute of Technology, Atlanta, GA 30332, USA. Electronic address: ssaxena30@gatech.edu.
L Andrew LyonPetit Institute for Biosciences and Bioengineering, Georgia Institute of Technology, Atlanta, GA 30332, USA; Schmid College of Science and Technology, Chapman University, Orange, CA 92866, USA. Electronic address: lyon@chapman.edu.

Funding

Microsphere-mediated differentiation of embryonic stem cellsR01GM088291 · NIGMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI MCDEVITT, TODD C · 2009 to 2013
$1.7M
NIGMS NIH HHS 1 R01 GM088291-01NIGMS NIH HHS R01 GM088291
6 · The paper itself

Abstract

We investigate the influence of microgel composition on phase behavior of binary microgel dispersions using poly(N-isopropylacrylamide) microgels cross-linked with 5 mol% and 1 mol% N,N'-methylenebis(acrylamide), or poly(N-isopropylmethacrylamide) microgels cross-linked with 5 mol% N,N'-methylenebis(acrylamide). We then explore the dispersion phase behavior in the context of microgel deposition at a planar interface. These results are then compared to the observed assembly of microgels at curved interfaces, in the form of raspberry-like patchy particles (RLPPs) consisting of a polystyrene core surrounded by a (two-component) microgel shell. Results suggest that microgel composition has a large influence on the ability of binary dispersions to coat planar and curved interfaces. In particular, we demonstrate that binary dispersions of microgels containing higher cross-linker content exhibit decreased packing densities that are very pronounced at a curved interface. To enhance packing density we also explore the use of a two-step coating process to fabricate RLPPs with enhanced control over topography. Development of these complex vehicles is potentially beneficial in the modulation of biological systems where spatial and temporal presentation of molecules can have a large influence on cellular behavior.

Indexed as

AcrylamidesAcrylic ResinsCross-Linking ReagentsDrug Delivery SystemsGelsParticle SizePhase TransitionPolystyrenesSurface PropertiesTemperatureAcrylamidesAcrylic ResinsCross-Linking ReagentsGelsN,N'-methylenebisacrylamidepoly-N-isopropylacrylamidePolystyrenesHeteroaggregationMicrogel phase behaviorMulti-functional delivery vehicles

Identifiers

PMID26057600
PMCPMC4475458

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.