ArticleBlood transfusion = Trasfusione del sangue2015
Sample stability for complete blood cell count using the Sysmex XN haematological analyser.
Article in Blood transfusion = Trasfusione del sangue, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- How Long can we Store Blood Samples: A Systematic Review and Meta-Analysis.EBioMedicine · 2017Pooled it
- Hemoscreen Point-of-Care Analyzer Compared With Sysmex XN-1000 for Complete Blood Count in Pediatric Inpatients Aged 2 Months to 17 Years.International journal of laboratory hematology · 2026Article
- Effects of different blood storage conditions on leukocytes cell population data using the Sysmex XN hematological analyzer.Biochemia medica · 2026Article
- Machine learning and AI-Assisted red blood cell morphology analysis for effective thalassemia screening.Annals of hematology · 2026Article
- Time stability of Intensive Care Infection Score (ICIS) as a cellular hematology biomarker for infection in critically ill patients.Scientific reports · 2026Article
- Predicting the dynamics of organ failure in patients with acute pancreatitis depending on the mean platelet volume.Surgery open science · 2024Article
- Red blood cell distribution width: the importance of preanalytical and analytical phase variables.Wiener klinische Wochenschrift · 2023Article
- Red Blood Cell Distribution Width as a Biomarker in Type 2 Diabetes Mellitus: Technical Notes [Letter].Diabetes, metabolic syndrome and obesity : targets and therapy · 2023Article
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- Analyte stability, instrumentation, and the red blood cell distribution width: comments on "Red blood cell distribution width and tumor necrosis factor‑α for the early prediction of coronary artery lesion in Kawasaki disease: a retrospective study". Eur J Pediatr. 2021 Sep 7.doi: 10.1007/s00431-021-04,252-3.European journal of pediatrics · 2022Article
- The 2000HIV study: Design, multi-omics methods and participant characteristics.Frontiers in immunology · 2022Article
- Association of systemic inflammation indices with visual field loss progression in patients with primary angle-closure glaucoma: potential biomarkers for 3P medical approaches.The EPMA journal · 2021Article
- Stability of hematological analytes during 48 hours storage at three temperatures using Cell-Dyn hematology analyzer.Journal of medical biochemistry · 2021Article
- Common and Novel Markers for Measuring Inflammation and Oxidative Stress Ex Vivo in Research and Clinical Practice-Which to Use Regarding Disease Outcomes?Antioxidants (Basel, Switzerland) · 2021Review
- Preliminary assessment of the new Sysmex XN parameter Iron-Def for identifying iron deficiency.Blood transfusion = Trasfusione del sangue · 2020Article
- FinDonor 10 000 study: a cohort to identify iron depletion and factors affecting it in Finnish blood donors.Vox sanguinis · 2020Article
- Diagnostic Role of Mean-Platelet Volume in Acute Pulmonary Embolism: A Meta-analysis and Systematic Review.Clinical medicine insights. Circulatory, respiratory and pulmonary medicine · 2020Article
- Storage stability of commonly used haematological parameters at 33 °C: Electronic supplementary material available online for this article.Biochemia medica · 2018Article
- The stability of quantitative blood count parameters using the ADVIA 2120i hematology analyzer.Practical laboratory medicine · 2016Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSample stability is a crucial aspect for the quality of results of a haematology laboratory. This study was conducted to investigate the reliability of haematological testing using Sysmex XN in samples stored for up to 24 h at different temperatures. MATERIALS AND
methodsHaematological tests were performed on whole blood samples collected from 16 ostensibly healthy outpatients immediately after collection and 3 h, 6 h or 24 h afterwards, with triple aliquots kept at room temperature, 4 °C or 37 °C.
resultsNo meaningful bias was observed after 3 h under different storage conditions, except for red blood cell distribution width (RDW) and platelet count (impedance technique, PLT-I) at 37 °C. After 6 h, meaningful bias was observed for mean corpuscular haemoglobin (MCH) and mean corpuscular volume (MCV) at room temperature, red blood cell (RBC) count, mean corpuscular haemoglobin concentration (MCHC), MCH, MCV and PLT-I at 4 °C, and RBC, RDW, MCHC, MCH and PLT-I at 37 °C. After 24 h, a meaningful bias was observed for MCHC, MCV, platelet count (fluorescent technique, PLT-F) and mean platelet volume (MPV) at room temperature, MCHC, MCV, PLT-I and MPV at 4 °C, and all parameters except RBC count and MPV at 37 °C. DISCUSSION: Great caution should be observed when analysing results of haematological tests conducted more than 3 h after sample collection.
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