Evidence map›Paper›PMID 26057408›Full record

ReviewJournal of clinical neurophysiology : official publication of the American Electroencephalographic Society2015

Could EEG Monitoring in Critically Ill Children Be a Cost-effective Neuroprotective Strategy?

Nicholas S Abend, Alexis A Topjian, Sankey Williams

Open access · greenAbstract readReview
In one paragraph

Review in Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 22 citations in OpenAlex.

  1. Continuous electroencephalography in the intensive care unit: A critical review and position statement from an Australian and New Zealand perspective.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Nicholas S AbendDepartments of *Neurology, †Pediatrics and ‡Anesthesia and Critical Care Medicine, The Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, U.S.A.; §Department of Medicine, the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, U.S.A.; and ‖Department of Health Care Management, the Wharton School at the University of Pennsylvania, Philadelphia, Pennsylvania, U.S.A.
Alexis A Topjian
Sankey Williams
Children's Hospital of Philadelphia · USPediatrics and Genetics · USUniversity of Pennsylvania · US

Funding

Non-convulsive seizures in critically ill children:physiology and outcomeK23NS076550 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI ABEND, NICHOLAS SCOTT · 2011 to 2015
$877k
Prompt Diagnosis and Treatment of Subclinical Seizures After Cardiac ArrestK23NS075363 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI TOPJIAN, ALEXIS A. · 2012 to 2016
$874k
NINDS NIH HHS K23 NS075363NINDS NIH HHS K23 NS076550
6 · The paper itself

Abstract

purposeElectrographic status epilepticus (ESE) in critically ill children is associated with unfavorable functional outcomes, but identifying candidates for ESE management requires resource-intense EEG monitoring. A cost-effectiveness analysis was performed to estimate how much ESE identification and management would need to improve patient outcomes to make EEG monitoring strategies a good value.

methodsA decision tree was created to examine the relationships among variables important to deciding whether to perform EEG monitoring. Variable costs were estimated from their component parts, outcomes were estimated in quality-adjusted life-years, and incremental cost-effectiveness ratios were calculated to compare the relative values using four alternative EEG monitoring strategies that varied by monitoring duration.

resultsForty-eight hours of EEG monitoring would be worth its cost if ESE identification and management improved patient outcomes by ≥7%. If ESE identification and management improved patient outcomes by 3% to 6%, then 24 or 48 hours of EEG monitoring would be worth the cost depending on how much decision makers were willing to pay per quality-adjusted life-year gained. If ESE identification and management improved outcomes by as little as 3%, then 24 hours of EEG monitoring would be worth the cost.

conclusionsEEG monitoring has the potential to be cost-effective if ESE identification and management improves patient outcomes by as little as 3%.

Indexed as

Cost-Benefit AnalysisElectroencephalographyChildCritical IllnessHumansStatus Epilepticus

Identifiers

PMID26057408
PMCPMC4668222
OpenAlexW635209063

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.