ArticlePloS one2015
Enhanced Heavy Metal Tolerance and Accumulation by Transgenic Sugar Beets Expressing Streptococcus thermophilus StGCS-GS in the Presence of Cd, Zn and Cu Alone or in Combination.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 83 citations in OpenAlex.
- Plant-Microbe-Assisted Approaches for Remediating Heavy Metals and Organic Pollutant Contamination in Electronic Waste Dump Sites.ACS omega · 2026Review
- Advances in Beet (Plants (Basel, Switzerland) · 2025Review
- Assessment of Genetic Diversity and Population Structure of Exotic Sugar Beet (Plants (Basel, Switzerland) · 2024Article
- Review
- An Insight into the Abiotic Stress Responses of Cultivated Beets (Plants (Basel, Switzerland) · 2021Review
- Metal and Metalloid Toxicity in Plants: An Overview on Molecular Aspects.Plants (Basel, Switzerland) · 2021Review
- Recent Developments in Microbe-Plant-Based Bioremediation for Tackling Heavy Metal-Polluted Soils.Frontiers in microbiology · 2021Review
- Phytoextraction of Heavy Metals: A Promising Tool for Clean-Up of Polluted Environment?Frontiers in plant science · 2018Review
- Overexpression of RsMYB1 Enhances Anthocyanin Accumulation and Heavy Metal Stress Tolerance in Transgenic Petunia.Frontiers in plant science · 2018Article
- Glutathione homeostasis and Cd tolerance in the Arabidopsis sultr1;1-sultr1;2 double mutant with limiting sulfate supply.Plant cell reports · 2016Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Phytoremediation is a promising means of ameliorating heavy metal pollution through the use of transgenic plants as artificial hyperaccumulators. A novel Streptococcus thermophilus γ-glutamylcysteine synthetase-glutathione synthetase (StGCS-GS) that synthesizes glutathione (GSH) with limited feedback inhibition was overexpressed in sugar beet (Beta vulgaris L.), yielding three transgenic lines (s2, s4 and s5) with enhanced tolerance to different concentrations of cadmium, zinc and copper, as indicated by their increased biomass, root length and relative growth compared with wild-type plants. Transgenic sugar beets accumulated more Cd, Zn and Cu ions in shoots than wild-type, as well as higher GSH and phytochelatin (PC) levels under different heavy metal stresses. This enhanced heavy metal tolerance and increased accumulation were likely due to the increased expression of StGCS-GS and consequent overproduction of both GSH and PC. Furthermore, when multiple heavy metal ions were present at the same time, transgenic sugar beets overexpressing StGCS-GS resisted two or three of the metal combinations (50 μM Cd-Zn, Cd-Cu, Zn-Cu and Cd-Zn-Cu), with greater absorption in shoots. Additionally, there was no obvious competition between metals. Overall, the results demonstrate the explicit role of StGCS-GS in enhancing Cd, Zn and Cu tolerance and accumulation in transgenic sugar beet, which may represent a highly promising new tool for phytoremediation.
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