Evidence map›Paper›PMID 26056479›Full record

ArticleOncoTargets and therapy2015

Anaplastic lymphoma kinase-positive anaplastic large-cell lymphoma with involvement of the urinary bladder: a case report and review of literature.

Xiaoqin Liang, Yingmei Wang, Jinsong Zhang, Hong Cheng, Jinsui Wang, Yamei Dang, Haomin Li, Ru Zhou, Jing Zhang, Qing Qiao

Open access · goldAbstract readCase Reports
In one paragraph

Article in OncoTargets and therapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Xiaoqin LiangState Key Laboratory of Tumor Biology, Department of Pathology, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, People's Republic of China ; Department of Pathology, Gansu Provincial People's Hospital, Lanzhou, Gansu, People's Republic of China.
Yingmei WangState Key Laboratory of Tumor Biology, Department of Pathology, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, People's Republic of China.
Jinsong ZhangDepartment of Radiology, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, People's Republic of China.
Hong ChengState Key Laboratory of Tumor Biology, Department of Pathology, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, People's Republic of China.
Jinsui WangDepartment of Pathology, Gansu Provincial People's Hospital, Lanzhou, Gansu, People's Republic of China.
Yamei DangDepartment of Pathology, Gansu Provincial People's Hospital, Lanzhou, Gansu, People's Republic of China.
Haomin LiState Key Laboratory of Tumor Biology, Department of Pathology, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, People's Republic of China ; Department of Neurosurgery, First affiliated Hospital, China Medical University, Shenyang, Liaoning, People's Republic of China.
Ru ZhouState Key Laboratory of Tumor Biology, Department of Pathology, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, People's Republic of China.
Jing ZhangState Key Laboratory of Tumor Biology, Department of Pathology, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, People's Republic of China.
Qing QiaoDepartment of General Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, People's Republic of China.
Air Force Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a unique case of anaplastic large-cell lymphoma (ALCL) involving the urinary bladder in a 22-year-old man. The patient presented with left lower back pain for 4 weeks. The computed tomography (CT) scan demonstrated an exophytic nodule on the left bladder wall and abdominopelvic lymphadenopathy. Histologically, a population of large pleomorphic cells extensively infiltrated the lamina propria of the bladder. These cells were diffusely and strongly immunoreactive for CD30, ALK, EMA, and vimentin, but were negative for AE1/AE3, CK20, CK7, CK5/6, P63, SMA, HMB-45, pan-Melan, S-100, Myo D1, synaptophysin, CD56, desmin, CD15, CD20, Pax-5, and CD3. Few cells exhibited positive immunohistochemical staining of CD45. The patient underwent cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) regime of chemotherapy and achieved a complete remission after four cycles. This case is the tenth documented case of systemic ALCL involving urinary bladder. Due to its rarity, it is important to be aware of the features of ALCL in bladder, and make prompt and accurate diagnosis.

Indexed as

anaplastic large-cell lymphomaanaplastic lymphoma kinaseurinary bladder

Identifiers

PMID26056479
PMCPMC4446009
OpenAlexW1826536148

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.