Evidence map›Paper›PMID 26056471›Full record

ArticleNutrition and metabolic insights2015

Hemoglobin and Ferritin Concentrations in Subjects with Metabolic Syndrome.

Adewumi Adediran, Ebele Uche, Akinsegun Akinbami, Akin Dada, Tamunomieibi Wakama, Dapus Damulak, Sarah Ajibola, Oluwakemi Okwegbuna

Open access · goldAbstract read
In one paragraph

Article in Nutrition and metabolic insights, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Adewumi AdediranDepartment of Haematology and Blood Transfusion, College of Medicine, University of Lagos, Lagos, Nigeria.
Ebele UcheDepartment of Haematology and Blood Transfusion, Lagos State University Teaching Hospital, Ikeja, Lagos, Nigeria.
Akinsegun AkinbamiDepartment of Haematology and Blood Transfusion, Lagos State University Teaching Hospital, Ikeja, Lagos, Nigeria.
Akin DadaDepartment of Medicine, Lagos State University Teaching Hospital, Ikeja, Lagos, Nigeria.
Tamunomieibi WakamaDepartment of Haematology and Blood Transfusion, National Hospital, Abuja, Nigeria.
Dapus DamulakDepartment of Haematology and Blood Transfusion, Jos University Teaching Hospital, Jos, Nigeria.
Sarah AjibolaDepartment of Haematology, Ben Carson School of Medicine, Babcock University, Ilisan-Remo, Ogun State, Nigeria.
Oluwakemi OkwegbunaDepartment of Haematology and Blood Transfusion, Lagos University Teaching Hospital, Lagos, Nigeria.
Lagos State University Teaching Hospital · NGJos University Teaching Hospital · NGLagos University Teaching Hospital · NGNational Hospital Abuja · NGUniversity of Lagos · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMetabolic syndrome (MetS), a clinical condition characterized by insulin resistance, glucose intolerance, dyslipidemia, hypertension, and obesity, has been linked with raised levels of serum ferritin (Sfr) concentrations.

objectivesThis study was carried out to compare hemoglobin (Hb) and Sfr concentrations in patients with MetS, regular donors and first-time donors. MATERIALS AND

methodsA total of 102 subjects who were between 18 and 60 years were enrolled for the study. They were divided into three groups. The first group (n = 20) was made up of 5 males and 15 females, all who met the criteria that define MetS. The second group (n = 52; M = 34, F = 18) were regular donors, while the last group (n = 30; M = 16, F = 14) were first-time donors or those who had not donated before. Following an overnight fast, 20 mL of venous blood was drawn from each subject. About 5 mL of this was put into sodium ethylenediaminetetraacetate (EDTA) specimen bottles for the full blood count parameters with Sysmex KX-21N hematology analyzer (made in Japan). The remaining 15 mL had serum separated for Sfr assay using enzyme-linked immunosorbent assay (ELISA) with a commercial assay kit manufactured by Teco Diagnostics.

resultsSignificant difference was found in the mean Sfr concentration of subjects with MetS (163 ± 136.92 ng/mL) and regular donors (41.46 ± 40.33 ng/mL), P = 0.001. The mean Sfr concentrations of subjects with MetS (163 ± 136.92 ng/mL) were also higher than that of first-time donors (102.46 ± 80.26 ng/mL), but it was not statistically significant, P = 0.053. The Hb concentrations of the three groups were not significantly different.

conclusionSfr concentrations of regular donors were lower than that of subjects with MetS and first-time donors. The difference between regular donors and subjects with MetS was statistically significant. However, there is no significant difference in the Hb concentrations in the three groups. MetS is not associated with anemia or hyperferritinemia.

Indexed as

dyslipidemiaferritininsulin resistancemetabolic syndrome

Identifiers

PMID26056471
PMCPMC4445885
OpenAlexW1492678672

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.