ArticleSubstance abuse : research and treatment2015
Emergency Department Visits Involving Misuse and Abuse of the Antipsychotic Quetiapine: Results from the Drug Abuse Warning Network (DAWN).
Article in Substance abuse : research and treatment, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 37 citations in OpenAlex.
- Acute Quetiapine Intoxication: Relationship Between Ingested Dose, Serum Concentration and Clinical Presentation-Structured Literature Review and Analysis.Journal of xenobiotics · 2024Review
- Article
- Association between Prescribing and Intoxication Rates for Selected Psychotropic Drugs: A Longitudinal Observational Study.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Prescription patterns of quetiapine for multiple drug abuse, depression, and psychosis: A retrospective study.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023Article
- Patterns of suboptimal antipsychotic use and misuse in Australia: What can routinely collected data tell us?British journal of clinical pharmacology · 2023Article
- Overdose and off-label psychotropic prescribing in patients with borderline personality disorder: A retrospective series.Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists · 2023Observational
- Quetiapine and olanzapine misuse prevalence in a US general population sample.The mental health clinician · 2023Article
- Antipsychotic Abuse, Dependence, and Withdrawal in the Pediatric Population: A Real-World Disproportionality Analysis.Biomedicines · 2022Article
- Quetiapine-Induced Place Preference in Mice: Possible Dopaminergic Pathway.Pharmaceuticals (Basel, Switzerland) · 2021Article
- Quetiapine, Misuse and Dependency: A Case-Series of Questions to a Norwegian Network of Drug Information Centers.Drug, healthcare and patient safety · 2021Article
- Characteristics of voluntary reporting of adverse drug events related to antipsychotics in Australia: 14-year analysis.Therapeutic advances in drug safety · 2021Article
- Comparison of Quetiapine Abuse and Misuse Reports to the FDA Adverse Event Reporting System With Other Second-Generation Antipsychotics.Substance abuse : research and treatment · 2019Article
- Abuse of Prescription Drugs in the Context of Novel Psychoactive Substances (NPS): A Systematic Review.Brain sciences · 2018Review
- Intentional Recreational Abuse of Quetiapine Compared to Other Second-generation Antipsychotics.The western journal of emergency medicine · 2017Article
- The antipsychotic story: changes in prescriptions and overdose without better safety.British journal of clinical pharmacology · 2016Article
- Quetiapine Misuse and Abuse: Is it an Atypical Paradigm of Drug Seeking Behavior?Journal of research in pharmacy practiceReview
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Case reports in medical literature suggest that the atypical antipsychotic quetiapine, a medication not previously considered to have abuse potential, is now being subject to misuse and abuse (MUA; ie, taken when not prescribed for them or used in a way other than instructed by their health professional). Here we present systematic, nationally representative data from the 2005 to 2011 Drug Abuse Warning Network (DAWN) for prevalence of emergency department (ED) visits among the U.S. general population involving quetiapine and related to MUA, suicide attempts, and adverse reactions. Nationally, quetiapine-related ED visits increased 90% between 2005 and 2011, from 35,581 ED visits to 67,497. DAWN data indicate that when used without medical supervision for recreational/self-medication purposes, quetiapine poses health risks for its users, especially among polydrug users and women. These findings suggest that the medical and public health communities should increase vigilance concerning this drug and its potential for MUA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.