ArticleProceedings of the National Academy of Sciences of the United States of America2015
Transmission potential of Rickettsia felis infection by Anopheles gambiae mosquitoes.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
75 citing papers in PubMed, 3 syntheses or guidelines pooled it, 147 citations in OpenAlex.
- Fungal microbiota diversity inWellcome open research · 2026Pooled it
- Insecticide resistance and the role of target-site insensitivity mutations among malaria vectors in China: A systematic review and meta-analysis.Parasites & vectors · 2025Pooled it
- A need for null models in understanding disease transmission: the example of Mycobacterium ulcerans (Buruli ulcer disease).FEMS microbiology reviews · 2022Pooled it
- Bacterial and Fungal Microbiota in Anopheles darlingi Exhibit Differences in Diversity Across Three Main Colombian Malaria-endemic Regions.Microbial ecology · 2026Article
- Sympatric Occurrence ofMicroorganisms · 2026Article
- Sand fly endosymbionts in Kenya: Rickettsia and Wolbachia associations with Leishmania and detection of Rickettsia africae.Parasites & vectors · 2026Article
- Mosquitoes as vector-based sentinels for tracking bacterial pathogens and antimicrobial resistance in the environment.Frontiers in microbiology · 2026Review
- Rickettsia felis meningoencephalitis in a 10-year-old child: a case report and literature review.BMC pediatrics · 2025Review
- Leveraging microbial ecology for mosquito-borne disease control.Trends in parasitology · 2025Review
- Assessment of MALDI-TOF MS for Arthropod Identification Based on Exuviae Spectra Analysis.Biological procedures online · 2025Article
- Review
- Rickettsiosis Infections in Sarawak: Epidemiological Insights and Public Health Strategies.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025Review
- Aedes albopictus saliva contains a richer microbial community than the midgut.Parasites & vectors · 2024Article
- Article
- Investigating the etiologies of non-malarial febrile illness in Senegal using metagenomic sequencing.Nature communications · 2024Article
- Prediction of potential drug targets and key inhibitors (ZINC67974679, ZINC67982856, and ZINC05668040) againstFrontiers in veterinary science · 2024Article
- The detection of zoonotic microorganisms inFrontiers in veterinary science · 2024Article
- Tick-Borne Diseases of Humans and Animals in West Africa.Pathogens (Basel, Switzerland) · 2023Review
- Molecular Detection ofVeterinary sciences · 2023Article
- Deep learning and wing interferential patterns identify Anopheles species and discriminate amongst Gambiae complex species.Scientific reports · 2023Article
15 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A growing number of recent reports have implicated Rickettsia felis as a human pathogen, paralleling the increasing detection of R. felis in arthropod hosts across the globe, primarily in fleas. Here Anopheles gambiae mosquitoes, the primary malarial vectors in sub-Saharan Africa, were fed with either blood meal infected with R. felis or infected cellular media administered in membrane feeding systems. In addition, a group of mosquitoes was fed on R. felis-infected BALB/c mice. The acquisition and persistence of R. felis in mosquitoes was demonstrated by quantitative PCR detection of the bacteria up to day 15 postinfection. R. felis was detected in mosquito feces up to day 14. Furthermore, R. felis was visualized by immunofluorescence in salivary glands, in and around the gut, and in the ovaries, although no vertical transmission was observed. R. felis was also found in the cotton used for sucrose feeding after the mosquitoes were fed infected blood. Natural bites from R. felis-infected An. gambiae were able to cause transient rickettsemias in mice, indicating that this mosquito species has the potential to be a vector of R. felis infection. This is particularly important given the recent report of high prevalence of R. felis infection in patients with "fever of unknown origin" in malaria-endemic areas.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.