Evidence map›Paper›PMID 26055750›Full record

ArticleThe American journal of tropical medicine and hygiene2015

Antimicrobial Disk Susceptibility Testing of Leptospira spp. Using Leptospira Vanaporn Wuthiekanun (LVW) Agar.

Vanaporn Wuthiekanun, Premjit Amornchai, Sayan Langla, Nicholas J White, Nicholas P J Day, Direk Limmathurotsakul, Sharon J Peacock

Abstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. A Scoping Review of Antimicrobial Therapy inAnimals : an open access journal from MDPI · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Antimicrobial Susceptibility Testing ofThe American journal of tropical medicine and hygiene · 2019
    Article
  9. Article
  10. Antimicrobial Resistance inMicrobiology spectrum · 2018
    Review
  11. Article
  12. Quality controls for antimicrobial disk diffusion testing on Leptospira Vanaporn Wuthiekanun agar.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Vanaporn Wuthiekanun
Premjit Amornchai
Sayan Langla
Nicholas J White
Nicholas P J Day
Direk Limmathurotsakul
Sharon J Peacock

Funding

Wellcome Trust 089275/Z/09/ZWellcome Trust 093956
6 · The paper itself

Abstract

Leptospira Vanaporn Wuthiekanun (LVW) agar was used to develop a disk diffusion assay for Leptospira spp. Ten pathogenic Leptospira isolates were tested, all of which were susceptible to 17 antimicrobial agents (amoxicillin/clavulanic acid, amoxicillin, azithromycin, cefoxitin, ceftazidime, ceftriaxone, chloramphenicol, ciprofloxacin, clindamycin, doripenem, doxycycline, gentamicin, linezolid, nitrofurantoin, penicillin, piperacillin/tazobactam, and tetracycline). All 10 isolates had no zone of growth inhibition for four antimicrobials (fosfomycin, nalidixic acid, rifampicin, and trimethoprim/sulfamethoxazole). Of the ten Leptospira, seven had a growth inhibition zone of ≤ 21 mm for aztreonam, the zone diameter susceptibility break point for Enterobacteriaceae. This assay could find utility as a simple screening method during the epidemiological surveillance of antimicrobial resistance in Leptospira spp.

Indexed as

Drug Resistance, Multiple, BacterialAnti-Bacterial AgentsCiprofloxacinGentamicinsLeptospiraMicrobial Sensitivity TestsPenicillanic AcidPiperacillinPiperacillin, Tazobactam Drug CombinationRifampinTrimethoprim, Sulfamethoxazole Drug CombinationAnti-Bacterial AgentsCiprofloxacinGentamicinsPenicillanic AcidPiperacillinPiperacillin, Tazobactam Drug CombinationRifampinTrimethoprim, Sulfamethoxazole Drug Combination

Identifiers

PMID26055750
PMCPMC4530741

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.