Evidence map›Paper›PMID 26055742›Full record

ArticleThe American journal of tropical medicine and hygiene2015

Outbreak of Human Brucellosis from Consumption of Raw Goats' Milk in Penang, Malaysia.

Kar Nim Leong, Ting Soo Chow, Peng Shyan Wong, Siti Hawa Hamzah, Norazah Ahmad, Chin Chin Ch'ng

Abstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Omp19 EnablesFrontiers in immunology · 2019
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kar Nim LeongPenang General Hospital, Georgetown, Penang, Malaysia; Institute of Medical Research, Kuala Lumpur Federal Territory, Malaysia; Clinical Research Center, Penang General Hospital, Georgetown, Penang, Malaysia karniml@gmail.com.
Ting Soo ChowPenang General Hospital, Georgetown, Penang, Malaysia; Institute of Medical Research, Kuala Lumpur Federal Territory, Malaysia; Clinical Research Center, Penang General Hospital, Georgetown, Penang, Malaysia.
Peng Shyan WongPenang General Hospital, Georgetown, Penang, Malaysia; Institute of Medical Research, Kuala Lumpur Federal Territory, Malaysia; Clinical Research Center, Penang General Hospital, Georgetown, Penang, Malaysia.
Siti Hawa HamzahPenang General Hospital, Georgetown, Penang, Malaysia; Institute of Medical Research, Kuala Lumpur Federal Territory, Malaysia; Clinical Research Center, Penang General Hospital, Georgetown, Penang, Malaysia.
Norazah AhmadPenang General Hospital, Georgetown, Penang, Malaysia; Institute of Medical Research, Kuala Lumpur Federal Territory, Malaysia; Clinical Research Center, Penang General Hospital, Georgetown, Penang, Malaysia.
Chin Chin Ch'ngPenang General Hospital, Georgetown, Penang, Malaysia; Institute of Medical Research, Kuala Lumpur Federal Territory, Malaysia; Clinical Research Center, Penang General Hospital, Georgetown, Penang, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the largest outbreak of brucellosis in Penang, Malaysia. Brucellosis is not endemic in this region. The index case was a 45-year-old goat farm owner presented with 3 weeks of fever, headache, severe lethargy, poor appetite, and excessive sweating. He claimed to have consumed unpasteurized goat's milk that he had also sold to the public. Tests were negative for tropical diseases (i.e., dengue fever, malaria, leptospirosis and scrub typhus) and blood culture showed no growth. Based on epidemiological clues, Brucella serology was ordered and returned positive. Over a period of 1 year, 79 patients who had consumed milk bought from the same farm were diagnosed with brucellosis. Two of these patients were workers on the farm. Four laboratory staff had also contracted the disease presumably through handling of the blood samples. The mean duration from onset of symptoms to diagnosis was 53 days with a maximum duration of 210 days. A combination treatment of rifampin and doxycycline for 6 weeks was the first line of treatment in 90.5% of patients. One-third of the patients had sequelae after recovering and 21% had a relapse. We highlight the importance of Brucellosis as a differential diagnosis when a patient has unexplained chronic fever.

Indexed as

Disease OutbreaksAdultAnimalsBrucella melitensisBrucellosisFemaleFoodborne DiseasesGoatsHumansMalaysiaMaleMiddle AgedMilk

Identifiers

PMID26055742
PMCPMC4559693

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.