Evidence map›Paper›PMID 26055385›Full record

ArticleAntimicrobial agents and chemotherapy2015

Relative Strengths of Promoters Provided by Common Mobile Genetic Elements Associated with Resistance Gene Expression in Gram-Negative Bacteria.

Muhammad Kamruzzaman, Jason D Patterson, Shereen Shoma, Andrew N Ginn, Sally R Partridge, Jonathan R Iredell

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. From Species to Genes: A New Diagnostic Paradigm.Antibiotics (Basel, Switzerland) · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Muhammad KamruzzamanCentre for Infectious Diseases and Microbiology, The Westmead Millennium Institute for Medical Research, The University of Sydney, Westmead Hospital, Westmead, New South Wales, Australia.
Jason D PattersonCentre for Infectious Diseases and Microbiology, The Westmead Millennium Institute for Medical Research, The University of Sydney, Westmead Hospital, Westmead, New South Wales, Australia.
Shereen ShomaCentre for Infectious Diseases and Microbiology, The Westmead Millennium Institute for Medical Research, The University of Sydney, Westmead Hospital, Westmead, New South Wales, Australia.
Andrew N GinnCentre for Infectious Diseases and Microbiology, The Westmead Millennium Institute for Medical Research, The University of Sydney, Westmead Hospital, Westmead, New South Wales, Australia.
Sally R PartridgeCentre for Infectious Diseases and Microbiology, The Westmead Millennium Institute for Medical Research, The University of Sydney, Westmead Hospital, Westmead, New South Wales, Australia.
Jonathan R IredellCentre for Infectious Diseases and Microbiology, The Westmead Millennium Institute for Medical Research, The University of Sydney, Westmead Hospital, Westmead, New South Wales, Australia jonathan.iredell@sydney.edu.au.
The University of Sydney · AUWestmead Hospital · AUWestmead Institute for Medical Research · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Comparison of green fluorescent protein expression from outward-facing promoters (POUT) of ISAba1, ISEcp1, and ISAba125 revealed approximate equivalence in strength, intermediate between PCS (strong) and PCWTGN-10 (weak) class 1 integron promoter variants, >30-fold stronger than POUT of ISCR1, and >5 times stronger than Ptac. Consistent with its usual role, PCWTGN-10 produces more mRNA from a "downstream" gfp gene transcriptionally linked to a "usual" PCWTGN-10-associated gene cassette than does POUT of ISAba1.

Indexed as

beta-LactamasesDNA Transposable ElementsDrug Resistance, BacterialEscherichia coliGene ExpressionGreen Fluorescent ProteinsKlebsiella pneumoniaePlasmidsPromoter Regions, Geneticbeta-LactamasesDNA Transposable ElementsGreen Fluorescent Proteins

Identifiers

PMID26055385
PMCPMC4505201
OpenAlexW1921969470

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.