Evidence map›Paper›PMID 26054605›Full record

ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2015

External validation of the Hospital-patient One-year Mortality Risk (HOMR) model for predicting death within 1 year after hospital admission.

Carl van Walraven, Finlay A McAlister, Jeffrey A Bakal, Steven Hawken, Jacques Donzé

Registry-linked trialAbstract readValidation Study
In one paragraph

Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04171830 (Use of an Automated Prospective Clinical Surveillance Tool to Drive Screening for Unmet Palliative Needs Among Patients in the Final Year of Life), which is not on this map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04171830 naenrolling by invitationnot on this mapstarted 2019, after this paper: background citation

Use of an Automated Prospective Clinical Surveillance Tool to Drive Screening for Unmet Palliative Needs Among Patients in the Final Year of Life

TypeinterventionalSponsorOttawa Hospital Research InstituteRan2019 to 2027Enrolled3,536ConditionsPalliative Therapy, Implementation Science, Screening, Terminal CareArmsmodified Hospital One-year Mortality Risk (mHOMR)
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The "surprise question" for predicting death in seriously ill patients: a systematic review and meta-analysis.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2017
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  14. Patient-physician language concordance and quality and safety outcomes among frail home care recipients admitted to hospital in Ontario, Canada.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Carl van WalravenDepartments of Medicine and of Epidemiology and Community Medicine, University of Ottawa (van Walraven), Ottawa, Ont.; Ottawa Hospital Research Institute (van Walraven, Hawken), Ottawa, Ont.; Department of Medicine, University of Alberta, and Alberta Innovates - Health Solutions (McAlister), Edmonton, Alta.; Health Research Methods and Analytics, Patient Health Outcomes Research and Clinical Effectiveness Unit, University of Alberta, and Alberta Strategy for Patient Oriented Research Support Unit (Bakal), Edmonton, Alta.; Division of General Internal Medicine, Bern University, Bern, Switzerland; Brigham & Women's Hospital and Harvard Medical School (Donzé), Boston, Mass. carlv@ohri.ca.
Finlay A McAlisterDepartments of Medicine and of Epidemiology and Community Medicine, University of Ottawa (van Walraven), Ottawa, Ont.; Ottawa Hospital Research Institute (van Walraven, Hawken), Ottawa, Ont.; Department of Medicine, University of Alberta, and Alberta Innovates - Health Solutions (McAlister), Edmonton, Alta.; Health Research Methods and Analytics, Patient Health Outcomes Research and Clinical Effectiveness Unit, University of Alberta, and Alberta Strategy for Patient Oriented Research Support Unit (Bakal), Edmonton, Alta.; Division of General Internal Medicine, Bern University, Bern, Switzerland; Brigham & Women's Hospital and Harvard Medical School (Donzé), Boston, Mass.
Jeffrey A BakalDepartments of Medicine and of Epidemiology and Community Medicine, University of Ottawa (van Walraven), Ottawa, Ont.; Ottawa Hospital Research Institute (van Walraven, Hawken), Ottawa, Ont.; Department of Medicine, University of Alberta, and Alberta Innovates - Health Solutions (McAlister), Edmonton, Alta.; Health Research Methods and Analytics, Patient Health Outcomes Research and Clinical Effectiveness Unit, University of Alberta, and Alberta Strategy for Patient Oriented Research Support Unit (Bakal), Edmonton, Alta.; Division of General Internal Medicine, Bern University, Bern, Switzerland; Brigham & Women's Hospital and Harvard Medical School (Donzé), Boston, Mass.
Steven HawkenDepartments of Medicine and of Epidemiology and Community Medicine, University of Ottawa (van Walraven), Ottawa, Ont.; Ottawa Hospital Research Institute (van Walraven, Hawken), Ottawa, Ont.; Department of Medicine, University of Alberta, and Alberta Innovates - Health Solutions (McAlister), Edmonton, Alta.; Health Research Methods and Analytics, Patient Health Outcomes Research and Clinical Effectiveness Unit, University of Alberta, and Alberta Strategy for Patient Oriented Research Support Unit (Bakal), Edmonton, Alta.; Division of General Internal Medicine, Bern University, Bern, Switzerland; Brigham & Women's Hospital and Harvard Medical School (Donzé), Boston, Mass.
Jacques DonzéDepartments of Medicine and of Epidemiology and Community Medicine, University of Ottawa (van Walraven), Ottawa, Ont.; Ottawa Hospital Research Institute (van Walraven, Hawken), Ottawa, Ont.; Department of Medicine, University of Alberta, and Alberta Innovates - Health Solutions (McAlister), Edmonton, Alta.; Health Research Methods and Analytics, Patient Health Outcomes Research and Clinical Effectiveness Unit, University of Alberta, and Alberta Strategy for Patient Oriented Research Support Unit (Bakal), Edmonton, Alta.; Division of General Internal Medicine, Bern University, Bern, Switzerland; Brigham & Women's Hospital and Harvard Medical School (Donzé), Boston, Mass.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPredicting long-term survival after admission to hospital is helpful for clinical, administrative and research purposes. The Hospital-patient One-year Mortality Risk (HOMR) model was derived and internally validated to predict the risk of death within 1 year after admission. We conducted an external validation of the model in a large multicentre study.

methodsWe used administrative data for all nonpsychiatric admissions of adult patients to hospitals in the provinces of Ontario (2003-2010) and Alberta (2011-2012), and to the Brigham and Women's Hospital in Boston (2010-2012) to calculate each patient's HOMR score at admission. The HOMR score is based on a set of parameters that captures patient demographics, health burden and severity of acute illness. We determined patient status (alive or dead) 1 year after admission using population-based registries.

resultsThe 3 validation cohorts (n = 2,862,996 in Ontario, 210 595 in Alberta and 66,683 in Boston) were distinct from each other and from the derivation cohort. The overall risk of death within 1 year after admission was 8.7% (95% confidence interval [CI] 8.7% to 8.8%). The HOMR score was strongly and significantly associated with risk of death in all populations and was highly discriminative, with a C statistic ranging from 0.89 (95% CI 0.87 to 0.91) to 0.92 (95% CI 0.91 to 0.92). Observed and expected outcome risks were similar (median absolute difference in percent dying in 1 yr 0.3%, interquartile range 0.05%-2.5%).

interpretationThe HOMR score, calculated using routinely collected administrative data, accurately predicted the risk of death among adult patients within 1 year after admission to hospital for nonpsychiatric indications. Similar performance was seen when the score was used in geographically and temporally diverse populations. The HOMR model can be used for risk adjustment in analyses of health administrative data to predict long-term survival among hospital patients.

Indexed as

HospitalizationModels, StatisticalMortalityAdolescentAdultAgedAlbertaBostonCohort StudiesComorbidityFemaleHumansLength of StayMaleMiddle AgedOntario

Identifiers

PMID26054605
PMCPMC4500693

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Registered trials

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