ArticleJournal of the American Society of Nephrology : JASN2016
Association of Body Mass Index with Patient-Centered Outcomes in Children with ESRD.
Article in Journal of the American Society of Nephrology : JASN, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed, 56 citations in OpenAlex.
- Association between estimated time with low glomerular filtration rate and access to transplant among youth with advanced chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2026Article
- Body cell mass estimation by whole body potassium counter and its association with protein energy wasting in Indian children with chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2025Article
- Survey of legislative frameworks and national recommendations governing paediatric maintenance haemodialysis in Europe.Pediatric nephrology (Berlin, Germany) · 2025Article
- Weight of evidence: reevaluating BMI criteria as a barrier for kidney transplantation in children.Pediatric nephrology (Berlin, Germany) · 2025Article
- Nutritional profile and infection-related hospital admissions in children with chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2025Article
- Body mass index in pediatric kidney transplant selection criteria.Pediatric nephrology (Berlin, Germany) · 2024Article
- Childhood Obesity: Insight into Kidney Involvement.International journal of molecular sciences · 2023Review
- Associations of longitudinal height and weight with clinical outcomes in pediatric kidney replacement therapy: results from the ESPN/ERA Registry.Pediatric nephrology (Berlin, Germany) · 2023Article
- Should Bariatric Surgery Play a Larger Role in the Management of Pediatric Patients with Severe Obesity and End-Stage Organ Disease?Obesity surgery · 2023Article
- Malnutrition Patterns in Children with Chronic Kidney Disease.Life (Basel, Switzerland) · 2023Review
- Malnutrition and immune cell subsets in children undergoing kidney transplantation.Pediatric transplantation · 2022Article
- Epidemiology of pediatric chronic kidney disease/kidney failure: learning from registries and cohort studies.Pediatric nephrology (Berlin, Germany) · 2022Review
- Assessment and management of obesity and metabolic syndrome in children with CKD stages 2-5 on dialysis and after kidney transplantation-clinical practice recommendations from the Pediatric Renal Nutrition Taskforce.Pediatric nephrology (Berlin, Germany) · 2022Review
- Monitoring dialysis adequacy: history and current practice.Pediatric nephrology (Berlin, Germany) · 2021Article
- Longitudinal outcomes of body mass index in overweight and obese children with chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2021Article
- Association Between Secondary Hyperparathyroidism and Body Composition in Pediatric Patients With Moderate and Advanced Chronic Kidney Disease.Frontiers in pediatrics · 2021Article
- Trends in Cardiovascular Mortality Among a Cohort of Children and Young Adults Starting Dialysis in 1995 to 2015.JAMA network open · 2020Article
- Trends in Living Donation by Race and Ethnicity Among Children With End-stage Renal Disease in the United States, 1995-2015.Transplantation direct · 2020Article
- Serum albumin and hospitalization among pediatric patients with end-stage renal disease who started dialysis therapy.Pediatric nephrology (Berlin, Germany) · 2019Article
- Association between BMI changes and mortality risk in children with end-stage renal disease.Pediatric nephrology (Berlin, Germany) · 2019Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Obesity is associated with less access to transplantation among adults with ESRD. To examine the association between body mass index at ESRD onset and survival and transplantation in children, we performed a retrospective analysis of children ages 2-19 years old beginning RRT from 1995 to 2011 using the US Renal Data System. Among 13,172 children, prevalence of obesity increased from 14% to 18%, whereas prevalence of underweight decreased from 12% to 9% during this period. Over a median follow-up of 7.0 years, 10,004 children had at least one kidney transplant, and 1675 deaths occurred. Risk of death was higher in obese (hazard ratio [HR], 1.17; 95% confidence interval [95% CI], 1.03 to 1.32) and underweight (HR, 1.26; 95% CI, 1.09 to 1.47) children than children with normal body mass indices. Obese and underweight children were less likely to receive a kidney transplant (HR, 0.92; 95% CI, 0.87 to 0.97; HR, 0.83; 95% CI, 0.78 to 0.89, respectively). Obese children had lower odds of receiving a living donor transplant (odds ratio, 0.85; 95% CI, 0.74 to 0.98) if the transplant occurred within 18 months of ESRD onset. Adjustment for transplant in a time-dependent Cox model attenuated the higher risk of death in obese but not underweight children (HR, 1.09; 95% CI, 0.96 to 1.24). Lower rates of kidney transplantation may, therefore, mediate the higher risk of death in obese children with ESRD. The increasing prevalence of obesity among children starting RRT may impede kidney transplantation, especially from living donors.
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