ArticleThe journal of nutrition, health & aging2015
A Study of the Applicability of GFR Evaluation Equations for an Elderly Chinese Population.
Article in The journal of nutrition, health & aging, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Comparison of the applicability of seven calculation equations of glomerular filtration rate among elderly people in China.International urology and nephrology · 2024Article
- Optimal Glomerular Filtration Rate Equations for Various Age Groups, Disease Conditions and Ethnicities in Asia: A Systematic Review.Journal of clinical medicine · 2023Review
- Comparison of Creatinine and Cystatin C to Estimate Renal Function in Geriatric and Frail Patients.Life (Basel, Switzerland) · 2022Article
- Article
- Plasma phenylalanine and tyrosine and their interactions with diabetic nephropathy for risk of diabetic retinopathy in type 2 diabetes.BMJ open diabetes research & care · 2020Article
- Evaluation of glomerular filtration rate by different equations in Chinese elderly with chronic kidney disease.International urology and nephrology · 2017Article
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Authors and funding
13 authors.
Funding
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Abstract
objectivesThis study screened current GFR evaluation equations that showed high accuracy for elderly populations and evaluated the applicability of these equations for an elderly Chinese population. MEASUREMENTS: A standard dual plasma sampling method (DPSM) of estimating 99mTc-diethylene triamine penta-acetic acid clearance was used to determine measured GFR (mGFR).
resultsComprehensive information was received for a total of 151 elderly individuals, with a mean mGFR of 65.39 ± 24.19 ml/min/1.73 m2. For the overall samples, the accuracy (P30), bias, absolute bias and interquartile ranges (IQRs) of the CKD2 (cystatin C(CysC)-serum creatinine(SCr)), CKD-EPI(CysC-SCr), Cockcroft-Gault(CG), CKD2(CysC), CKD-EPI(CysC), and Hoek equations were superior to c-aGFR3, c-aGFR4 and Grubb equation, Bland-Altman analysis also demonstrated a consistent result. Among elderly subjects with mGFR≥60 ml/min/1.73 m2, the CKD2 (CysC-SCr) and CKD-EPI (CysC-SCr) equations showed significantly higher correlations and accuracy than the other examined equations. Among elderly subjects with mGFR<60 ml/min/1.73 m2, only the CG equation showed an accuracy (P30) of greater than 70% and demonstrated higher precision than the other examined equations.
conclusionFor the elderly population, the CG, CKD2, CKD-EPI, and Hoek equations exhibited good accuracy. The CKD2(CysC-SCr) equation and CKD-EPI(CysC-SCr) equation demonstrated relatively high accuracy for evaluating elderly subjects with mGFR≥60 ml/min/1.73 m2, whereas the CG equation was more suitable for evaluating elderly subjects with mGFR<60 ml/min/1.73 m2.
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