ArticleThe journal of nutrition, health & aging2015
Lean Mass Appears to Be More Strongly Associated with Bone Health than Fat Mass in Urban Black South African Women.
Article in The journal of nutrition, health & aging, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- The association between body mass index and osteoporosis, with consideration of sex differences: a systematic review and dose-response meta-analysis.BMC musculoskeletal disorders · 2026Pooled it
- Trajectories of Nutritional Status and Cognitive Impairment among Older Taiwanese with Hip Fracture.The journal of nutrition, health & aging · 2017Trial
- Association between body composition and bone mineral density in community-dwelling older adults from Chile: a sex-stratified DXA-based cross-sectional study.BMC geriatrics · 2026Article
- The Cervical Vertebral Bone Quality Score Is a Novel Reliable Index Reflecting the Condition of Paraspinal Muscles and Predicting Loss of Cervical Lordosis After Open-Door Laminoplasty.Orthopaedic surgery · 2025Article
- Using QCT for the prediction of spontaneous age- and gender-specific thoracolumbar vertebral fractures and accompanying distant vertebral fractures.BMC musculoskeletal disorders · 2024Article
- Accelerometer-Measured Physical Activity Data Sets (Global Physical Activity Data Set Catalogue) That Include Markers of Cardiometabolic Health: Systematic Scoping Review.Journal of medical Internet research · 2023Article
- The Impact of Human Immunodeficiency Virus and Menopause on Bone Mineral Density: A Longitudinal Study of Urban-Dwelling South African Women.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2023Article
- Relationship between geriatric nutritional risk index and osteoporosis in type 2 diabetes in Northern China.BMC endocrine disorders · 2022Article
- Bone, fat, and muscle interactions in health and disease.Archives of endocrinology and metabolism · 2022Review
- Association between fat mass by bioelectrical impedance analysis and bone mass by quantitative ultrasound in relation to grip strength and serum 25-hydroxyvitamin D in postmenopausal Japanese women: the Unzen study.Journal of physiological anthropology · 2022Article
- The different correlations between obesity and osteoporosis after adjustment of static mechanical loading from weight and fat free mass.Journal of musculoskeletal & neuronal interactions · 2021Article
- Article
- Influence of Mediterranean Diet Adherence and Physical Activity on Bone Health in Celiac Children on a Gluten-Free Diet.Nutrients · 2021Article
- The association between serum vitamin D and body composition in South African HIV-infected women.Southern African journal of HIV medicine · 2021Article
- Determinants of Bone Health Status in a Multi-Ethnic Population in Klang Valley, Malaysia.International journal of environmental research and public health · 2020Article
- Magnesium Intake Predicts Bone Turnover in Postmenopausal Black South African Women.Nutrients · 2019Article
- Changes in food intake from 2005 to 2010 by a cohort of black rural and urban African men and women in the North West Province of South Africa: the PURE-NWP-SA study.Public health nutrition · 2018Article
- Accelerated nutrition transition in the North West Province of South Africa: results from the Prospective Urban and Rural Epidemiology (PURE-NWP-SA) cohort study, 2005 to 2010.Public health nutrition · 2018Article
- Association of serum uric acid levels with osteoporosis and bone turnover markers in a Chinese population.Acta pharmacologica Sinica · 2018Observational
- Lean Body Mass in the Prediction of Bone Mineral Density in Postmenopausal Women.BioResearch open access · 2018Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo examine the association between body composition (fat mass, lean mass and body mass index, BMI) and bone health (bone mineral density, BMD and fracture risk) in urban black South African women.
designA cross sectional study examining associations between body composition, dietary intake (food frequency questionnaire), habitual physical activity (Activity energy expenditure (AEE) measured using an accelerometer with combined heart rate monitor and physical activity questionnaire) and bone health (BMD using dual-energy X ray absorptiometry, DXA and fracture risk).
settingUrban community dwellers from Ikageng in the North-West Province of South Africa.
participantsOne hundred and eighty nine (189) healthy postmenopausal women aged ≥43 years.
resultsFat mass and lean mass were significantly associated with BMD and fracture risk when adjusted for potential confounders. However, lean mass and not fat mass remained significantly associated with femoral neck BMD (β = 0.49, p <0.001), spine BMD (β = 0.48, p< 0.0001) and hip BMD (β = 0.59, p< 0.0001). Lean mass was also negatively associated with fracture risk (β = -0.19 p =0.04) when both lean and fat mass were in the same model.
conclusionLean mass and fat mass were positively associated with femoral neck, spine and hip BMDs and negatively associated with fracture risk in urban black South African women. Our finding suggests that increasing lean mass rather than fat mass is beneficial to bone health. Our study emphasises the importance of positive lifestyle changes, intake of calcium from dairy and adequate weight to maintain and improve bone health of postmenopausal women.
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