Evidence map›Paper›PMID 26053216›Full record

ArticleEnvironmental science & technology2015

Human Serum from Urban and Rural Adolescents and Their Mothers Shows Exposure to Polychlorinated Biphenyls Not Found in Commercial Mixtures.

Wen Xin Koh, Keri C Hornbuckle, Peter S Thorne

Abstract read
In one paragraph

Article in Environmental science & technology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 74 citations in OpenAlex.

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  16. Review
  17. Distinguishing Aroclor and non-Aroclor sources to Chicago Air.The Science of the total environment · 2022
    Article
  18. Impact of Endocrine Disruptors upon Non-Genetic Inheritance.International journal of molecular sciences · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Wen Xin Koh†Interdisciplinary Graduate Program in Human Toxicology, ‡Department of Civil and Environmental Engineering, and §Department of Occupational and Environmental Health, The University of Iowa, Iowa City, Iowa 52242, United States.
Keri C Hornbuckle†Interdisciplinary Graduate Program in Human Toxicology, ‡Department of Civil and Environmental Engineering, and §Department of Occupational and Environmental Health, The University of Iowa, Iowa City, Iowa 52242, United States.
Peter S Thorne†Interdisciplinary Graduate Program in Human Toxicology, ‡Department of Civil and Environmental Engineering, and §Department of Occupational and Environmental Health, The University of Iowa, Iowa City, Iowa 52242, United States.
University of Iowa · US

Funding

Training CoreP42ES013661 · NIEHS · UNIVERSITY OF IOWA · PI HANS-JOACHIM LEHMLER · 2006 to 2026
$60.3M
Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Brandi Janssen · 1990 to 2026
$40.5M
NIEHS NIH HHS P30 ES005605NIEHS NIH HHS P42 ES013661NIEHS NIH HHS P42ES013661
6 · The paper itself

Abstract

Although polychlorinated biphenyls are no longer sold as commercial mixtures, they are still being produced through modern manufacturing processes. We have previously shown that non-Aroclor PCB 11 is prevalent in indoor and outdoor air and sediment and detected in human serum. Here we report the prevalence of non-Aroclor PCB congeners (≤0.20 wt % in Aroclor) in human serum collected from urban and rural adolescents and their mothers. We hypothesized that additional non-Aroclor congeners are present in serum. Sera were extracted and detected for 209 PCBs using gas chromatography-tandem mass spectrometry. A list of 70 non-Aroclor PCB congeners was determined by measurement of original Aroclors. PCB 11, 14, 35, and 209 are the major dominating and most frequently detected congeners. PCB 14 and 35 have not been previously reported for environmental matrices. Adolescents have significantly lower total non-Aroclor PCB concentrations than mothers in East Chicago (p < 0.001) and Columbus Junction (p = 0.008). There are significant differences in non-Aroclor PCBs between East Chicago community and Columbus Junction community (p < 0.001). Non-Aroclor PCBs represent an average of 10% (and up to 50%) of total PCBs measured in serum. An average of 50% (and up to 100%) of these concentrations may be attributed to aryl azo and phthalocyanine paint pigments.

Indexed as

MothersRural PopulationUrban PopulationAdolescentAdultAroclorsChicagoEnvironmental ExposureFemaleHumansMalePolychlorinated BiphenylsStatistics, NonparametricAroclorsPolychlorinated Biphenyls

Identifiers

PMID26053216
PMCPMC4774248
OpenAlexW2298582741

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.