ReviewHarvard review of psychiatry
Comorbidity Between Attention Deficit/Hyperactivity Disorder and Obsessive-Compulsive Disorder Across the Lifespan: A Systematic and Critical Review.
Review in Harvard review of psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 120 citations in OpenAlex.
- Executive Functioning, Family Accommodation, and Treatment Response in Youth with OCD and Comorbid ADHD in a Partial Hospital Program.Child psychiatry and human development · 2026Article
- Isolating transdiagnostic effects reveals specific genetic profiles in psychiatric disorders.JCPP advances · 2026Article
- Article
- Distinct clinical phenotypes of pediatric Obsessive-Compulsive Disorder with and without neurodevelopmental disorders: evidence for a neurodevelopmental continuum.Journal of neurodevelopmental disorders · 2025Article
- An Examination of Impulsivity and Metacognitions in Adolescents with Body-Focused Repetitive Behavior Disorders.Child psychiatry and human development · 2025Article
- Biological, Psychosocial, and Microbial Determinants of Childhood-Onset Obsessive-Compulsive Disorder: A Narrative Review.Children (Basel, Switzerland) · 2025Review
- Untangling the Threads: The Impact of Co-Occurring OCD and ADHD Symptoms for Black and/or Latiné Youth.Children (Basel, Switzerland) · 2025Article
- Are the Unified Protocols for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents as Effective for OCD as for Anxiety and Depression?Children (Basel, Switzerland) · 2025Article
- Quantitative EEG Insights Into A Hundred Adult ADHD Patients: A Deep Dive Into Test of Variables of Attention (TOVA) Correlations and Attention Dynamics.CNS neuroscience & therapeutics · 2025Article
- Executive Functioning, Internalizing and Externalizing Symptoms: Understanding Developmental Dynamics Through Panel Network Approaches.JAACAP open · 2024Article
- The impacts associated with having ADHD: an umbrella review.Frontiers in psychiatry · 2024Review
- Changes in Anxiety following Taste Education Intervention: Fussy Eating Children with and without Neurodevelopmental Disorders.Nutrients · 2023Article
- Picky Eating in Childhood: Associations With Obsessive-Compulsive Symptoms.Journal of pediatric psychology · 2022Article
- Cortico-amygdalar connectivity and externalizing/internalizing behavior in children with neurodevelopmental disorders.Brain structure & function · 2022Article
- Gender-Related Clinical Characteristics in Children and Adolescents with ADHD.Journal of clinical medicine · 2022Article
- Correlation research of susceptibility single nucleotide polymorphisms and the severity of clinical symptoms in attention deficit hyperactivity disorder.Frontiers in psychiatry · 2022Article
- The (Un)real Existence of ADHD-Criteria, Functions, and Forms of the Diagnostic Entity.Frontiers in sociology · 2022Article
- Developmental Trajectories of Pediatric Obsessive-Compulsive Symptoms.Research on child and adolescent psychopathology · 2021Article
- Obsessive Beliefs and Clinical Features in Patients with Comorbid Obsessive-Compulsive Disorder and Attention-Deficit/Hyperactivity Disorder.Psychiatry and clinical psychopharmacology · 2021Article
- Genetics of obsessive-compulsive disorder.Psychological medicine · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The concept of comorbidity between attention deficit/hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD) has been discussed for two decades. No review, however, has examined this question in light of the stark contrast in disorder-specific phenomenology and neurobiology. We review reported prevalence rates and the methodological, phenomenological, and theoretical issues concerning concomitant ADHD-OCD. Reported co-occurrence rates are highly inconsistent in the literature. Studies aimed at examining the potential for comorbidity have suffered from various methodological problems, including the existence of very few community samples, highly variable exclusionary criteria, and possible clinical misinterpretation of symptoms. Despite numerous studies suggesting an ADHD-OCD comorbidity, thus far etiological (i.e., genetic) backing has been provided only for a pediatric comorbidity. Additionally, inflated rates of ADHD-OCD co-occurrence may be mediated by the presence of tic disorders, and evidence of impaired neuronal maturational processes in pediatric OCD may lead to possibly transient phenotypical expressions that resemble ADHD symptomatology. Thus, clinicians are encouraged to consider the possibility that ADHD-like symptoms resulting from OCD-specific symptomatology may be misdiagnosed as ADHD. This suggestion may account for the lower co-occurrence rates reported in adolescents and adults and for the lack of a theoretical account for comorbidity in these age groups. Existing literature is summarized and critically reviewed, and recommendations are made for future research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.