Evidence map›Paper›PMID 26052709›Full record

ArticlePloS one2015

Breviscapine Injection Improves the Therapeutic Effect of Western Medicine on Angina Pectoris Patients.

Chuan Wang, Yafeng Li, Shoucui Gao, Daxin Cheng, Sihai Zhao, Enqi Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Targeting inflammation and oxidative stress for protection against ischemic brain injury in rats using cupressuflavone.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Article
  3. Ameliorative effect of scutellarin on acute alcohol brain injury in mice.Journal of Zhejiang University. Science. B · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chuan WangResearch Institute of Atherosclerotic Disease, Xi'an Jiaotong University Cardiovascular Research Center, Shaanxi, China; Department of Molecular Pathology, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Yamanashi, Japan.
Yafeng LiResearch Institute of Atherosclerotic Disease, Xi'an Jiaotong University Cardiovascular Research Center, Shaanxi, China.
Shoucui GaoResearch Institute of Atherosclerotic Disease, Xi'an Jiaotong University Cardiovascular Research Center, Shaanxi, China.
Daxin ChengResearch Institute of Atherosclerotic Disease, Xi'an Jiaotong University Cardiovascular Research Center, Shaanxi, China; The Third Affiliated Hospital of the School of Medicine, Xi'an Jiaotong University, Shaanxi, China.
Sihai ZhaoResearch Institute of Atherosclerotic Disease, Xi'an Jiaotong University Cardiovascular Research Center, Shaanxi, China.
Enqi LiuResearch Institute of Atherosclerotic Disease, Xi'an Jiaotong University Cardiovascular Research Center, Shaanxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To evaluate the beneficial and adverse effects of breviscapine injection in combination with Western medicine on the treatment of patients with angina pectoris. The Cochrane Central Register of Controlled Trials, Medline, Science Citation Index, EMBASE, the China National Knowledge Infrastructure, the Wanfang Database, the Chongqing VIP Information Database and the China Biomedical Database were searched to identify randomized clinical trials (RCTs) that evaluated the effects of Western medicine compared to breviscapine injection plus Western medicine on angina pectoris patients. The included studies were analyzed using RevMan 5.1.0 software. The literature search yielded 460 studies, wherein 16 studies matched the selection criteria. The results showed that combined therapy using Breviscapine plus Western medicine was superior to Western medicine alone for improving angina pectoris symptoms (OR=3.77, 95% Cl: 2.76~5.15) and also resulted in increased electrocardiogram (ECG) improvement (OR=2.77, 95% Cl: 2.16~3.53). The current evidence suggests that Breviscapine plus Western medicine achieved a superior therapeutic effect compared to Western medicine alone.

Indexed as

Angina PectorisFlavonoidsHumansInjectionsPublication BiasRandomized Controlled Trials as TopicUltrasonographybreviscapineFlavonoids

Identifiers

PMID26052709
PMCPMC4460136

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.