Evidence map›Paper›PMID 26052550›Full record

ArticleJournal of nature and science2015

A new way to detect the danger: Lysosomal cell death induced by a bacterial ribosomal protein.

Wenhan Zhu, Zhao-Qing Luo

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Journal of nature and science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. bioRxiv : the preprint server for biology · 2023
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Wenhan ZhuDepartment of Biological Sciences, Purdue University, West Lafayette, IN 47907, USA.
Zhao-Qing LuoDepartment of Biological Sciences, Purdue University, West Lafayette, IN 47907, USA.
Purdue University West Lafayette · US

Funding

Modulation of Host Vesicle Trafficking by Legionella pneumophilaK02AI085403 · NIAID · PURDUE UNIVERSITY · PI LUO, ZHAO-QING · 2010 to 2014
$556k
Probing novel innate immune detection mechanisms using an intracellular bacterialR21AI105714 · NIAID · PURDUE UNIVERSITY · PI LUO, ZHAO-QING · 2014 to 2015
$411k
Molecular Mechanisms of Host Function Exploitation by Type IV effectors of LegionR56AI103168 · NIAID · PURDUE UNIVERSITY · PI LUO, ZHAO-QING · 2013 to 2013
$327k
NIAID NIH HHS K02 AI085403NIAID NIH HHS R21 AI105714NIAID NIH HHS R56 AI103168
6 · The paper itself

Abstract

The death of immune cells in response to pathogens often dictates the outcome of an infection. In some contexts, pathogens specifically kill immune cells by producing highly potent toxins or by triggering host cell death pathways, thus ensuring successful infections. But for intracellular pathogens and viruses, the death of host cells normally is disastrous for their intracellular life cycle. Our recent experiments with the pathogen

Indexed as

apoptosiscaspasescathepsinsinnate immunityLegionella

Identifiers

PMID26052550
PMCPMC4457467
OpenAlexW1938989241

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.