Evidence map›Paper›PMID 26052361›Full record

ArticleCognitive neurodynamics2015

Monitoring depth of anesthesia using combination of EEG measure and hemodynamic variables.

R Shalbaf, H Behnam, H Jelveh Moghadam

Registry-linked trialAbstract read
In one paragraph

Article in Cognitive neurodynamics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02938325 (Monitoring Awareness and Pain Under Anesthesia Using a New EEG Based System), which is not on this map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02938325 unknown statusnot on this mapstarted 2017, after this paper: background citation

Monitoring Awareness and Pain Under Anesthesia Using a New EEG Based System

TypeobservationalSponsorRambam Health Care CampusRan2017 to 2024Enrolled90ConditionsAwareness Under Anesthesia
3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Anesthesia depth prediction from drug infusion history using hybrid AI.BMC medical informatics and decision making · 2025
    Article
  5. Article
  6. Review
  7. Observational
  8. Review
  9. Article
  10. Analyzing Electroencephalography (EEG) Waves Provides a Reliable Tool to Assess the Depth of Sevoflurane Anesthesia in Pediatric Patients.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

R ShalbafSchool of Electrical Engineering, Iran University of Science and Technology, Tehran, Iran.
H BehnamSchool of Electrical Engineering, Iran University of Science and Technology, Tehran, Iran.
H Jelveh MoghadamDepartment of Anesthesia, Shahid Beheshti University of Medical Science, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monitoring depth of anesthesia (DOA) via vital signs is a major ongoing challenge for anesthetists. A number of electroencephalogram (EEG)-based monitors such as the Bispectral (BIS) index have been proposed. However, anesthesia is related to central and autonomic nervous system functions whereas the EEG signal originates only from the central nervous system. This paper proposes an automated DOA detection system which consists of three steps. Initially, we introduce multiscale modified permutation entropy index which is robust in the characterization of the burst suppression pattern and combine multiscale information. This index quantifies the amount of complexity in EEG data and is computationally efficient, conceptually simple and artifact resistant. Then, autonomic nervous system activity is quantified with heart rate and mean arterial pressure which are easily acquired using routine monitoring machine. Finally, the extracted features are used as input to a linear discriminate analyzer (LDA). The method is validated with data obtained from 25 patients during the cardiac surgery requiring cardiopulmonary bypass. The experimental results indicate that an overall accuracy of 89.4 % can be obtained using combination of EEG measure and hemodynamic variables, together with LDA to classify the vital sign into awake, light, surgical and deep anesthetised states. The results demonstrate that the proposed method can estimate DOA more effectively than the commercial BIS index with a stronger artifact-resistance.

Indexed as

Depth of anesthesiaElectroencephalogram (EEG)Hemodynamic parametersPermutation entropy

Identifiers

PMID26052361
PMCPMC4454131

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.