ArticleBiotechnology for biofuels2015
Enzyme activity highlights the importance of the oxidative pentose phosphate pathway in lipid accumulation and growth of Phaeodactylum tricornutum under CO2 concentration.
Article in Biotechnology for biofuels, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 68 citations in OpenAlex.
- Microalgal cell factories for bioenergy and climate action: a circular bioeconomy roadmap.Microbial cell factories · 2026Review
- Review
- Transcriptomic Responses of the Marine DiatomEcology and evolution · 2026Article
- Genetic evidence for functions of Chloroplast CA in Pyropia yezoensis: decreased CCM but increased starch accumulation.Advanced biotechnology · 2024Article
- UV-A radiation increases biomass yield by enhancing energy flow and carbon assimilation in the edible cyanobacteriumApplied and environmental microbiology · 2024Article
- Overexpression of a novel gene (Pt2015) endows the commercial diatom Phaeodactylum tricornutum high lipid content and grazing resistance.Biotechnology for biofuels and bioproducts · 2022Article
- Metabolomic, proteomic and lactylated proteomic analyses indicate lactate plays important roles in maintaining energy and C:N homeostasis in Phaeodactylum tricornutum.Biotechnology for biofuels and bioproducts · 2022Article
- Culture Conditions Affect Antioxidant Production, Metabolism and Related Biomarkers of the MicroalgaeAntioxidants (Basel, Switzerland) · 2022Article
- RNA-seq analysis reveals genes related to photosynthetic carbon partitioning and lipid production inFrontiers in microbiology · 2022Article
- Proteomic and biochemical responses to different concentrations of COBiotechnology for biofuels · 2021Article
- Augmented CONature communications · 2021Article
- Gm6PGDH1, a Cytosolic 6-Phosphogluconate Dehydrogenase, Enhanced Tolerance to Phosphate Starvation by Improving Root System Development and Modifying the Antioxidant System in Soybean.Frontiers in plant science · 2021Article
- Article
- Elevated COMicrobial cell factories · 2019Article
- Provision of carbon skeleton for lipid synthesis from the breakdown of intracellular protein and soluble sugar in Phaeodactylum tricornutum under high COBMC biotechnology · 2019Article
- Carbon Orientation in the DiatomFrontiers in plant science · 2019Article
- Dual expression of plastidial GPAT1 and LPAT1 regulates triacylglycerol production and the fatty acid profile inBiotechnology for biofuels · 2018Article
- Modulation of lipid biosynthesis by stress in diatoms.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Review
- The dilemma for lipid productivity in green microalgae: importance of substrate provision in improving oil yield without sacrificing growth.Biotechnology for biofuels · 2016Review
- Transcriptome analysis reveals global regulation in response to CO2 supplementation in oleaginous microalga Coccomyxa subellipsoidea C-169.Biotechnology for biofuels · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRising CO2 concentration was reported to increase phytoplankton growth rate as well as lipid productivity. This has raised questions regarding the NADPH supply for high lipid synthesis as well as rapid growth of algal cells.
resultsIn this study, growth, lipid content, photosynthetic performance, the activity, and expression of key enzymes in Calvin cycle and oxidative pentose phosphate pathway (OPPP) were analyzed in the marine diatom Phaeodactylum tricornutum under three different CO2 concentrations (low CO2 (0.015 %), mid CO2 (atmospheric, 0.035 %) and high CO2 (0.15 %)). Both the growth rate and lipid content of P. tricornutum increased significantly under the high CO2 concentration. Enzyme activity and mRNA expression of three Calvin cycle-related enzymes (Rubisco, 3-phosphoglyceric phosphokinase (PGK), phosphoribulokinase (PRK)) were also increased under high CO2 cultivation, which suggested the enhancement of Calvin cycle activity. This may account for the observed rapid growth rate. In addition, high activity and mRNA expression of G6PDH and 6PGDH, which produce NADPH through OPPP, were observed in high CO2 cultured cells. These results indicate OPPP was enhanced and might play an important role in lipid synthesis under high CO2 concentration.
conclusionsThe oxidative pentose phosphate pathway may participate in the lipid accumulation in rapid-growth P. tricornutum cells in high CO2 concentration.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.