Evidence map›Paper›PMID 26051926›Full record

Trial reportJournal of the American Society of Hypertension : JASH2015

Regional and physician specialty-associated variations in the medical management of atherosclerotic renal-artery stenosis.

David A Folt, Kaleigh L Evans, Sravya Brahmandam, Wencan He, Pamela S Brewster, Shipeng Yu, Timothy P Murphy, Donald E Cutlip, Lance D Dworkin, Kenneth Jamerson and 9 more

Open access · greenAbstract readComparative StudyMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of the American Society of Hypertension : JASH, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Atherosclerotic renovascular disease - epidemiology, treatment and current challenges.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2017
    Review
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 11 institutions in 7 countries.

David A FoltDepartment of Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA.
Kaleigh L EvansDepartment of Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA.
Sravya BrahmandamDepartment of Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA.
Wencan HeDepartment of Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA.
Pamela S BrewsterDepartment of Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA.
Shipeng YuDepartment of Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA.
Timothy P MurphyDepartment of Diagnostic Imaging, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Donald E CutlipDepartment of Medicine, Harvard Clinical Research Institute, Boston, MA, USA.
Lance D DworkinDepartment of Diagnostic Imaging, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Kenneth JamersonDepartment of Medicine, University of Michigan, Ann Arbor, MI, USA.
William HenrichThe University of Texas Health Science Center, San Antonio, TX, USA.
Philip A KalraDepartment of Medicine, Salford Royal Hospital NHS Foundation Trust, Greater Manchester, United Kingdom.
Sheldon TobeSunnybrook and Women's College Health Sciences Centre, Toronto, Canada.
Ken ThomsonDepartment of Radiology, Alfred Hospital, Melbourne, Australia.
Andrew HoldenDepartment of Radiology, Auckland City Hospital, Auckland, New Zealand.
Brian L RaynerDepartment of Medicine, University of Cape Town/Groote Schuur Hospital, Cape Town, South Africa.
Liliana GrinfeldDepartment of Medicine, Universidad de Buenos Aires, Buenos Aires, Argentina.
Steven T HallerDepartment of Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA. Electronic address: Steven.haller@utoledo.edu.
Christopher J CooperDepartment of Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA.
University of Toledo · USBrown University · USAuckland City Hospital · NZBaim Institute for Clinical Research · USSalford Royal NHS Foundation Trust · GBSunnybrook Health Science Centre · CAThe Alfred Hospital · AUThe University of Texas Health Science Center at San Antonio · USUniversidad de Buenos Aires · ARUniversity of Cape Town · ZAUniversity of Michigan · US

Funding

CORAL: Clinical Coordinating CenterU01HL071556 · NHLBI · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI COOPER, CHRISTOPHER J · 2004 to 2013
$19.3M
CORAL: Data Coordinating CenterU01HL072737 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CUTLIP, DONALD · 2004 to 2013
$9.4M
CORAL: Economics and QOL Core LaboratoryU01HL072736 · NHLBI · SAINT LUKE'S HOSPITAL · PI COHEN, DAVID J · 2004 to 2013
$2.6M
CORAL Angiographic Core LaboratoryU01HL072735 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI MATSUMOTO, ALAN H. · 2004 to 2010
$1.4M
Coral: Central GFR and Biochemistry LaboratoryU01HL072734 · NHLBI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI STEFFES, MICHAEL W. · 2004 to 2012
$1.3M
NHLBI NIH HHS 5U01HL071556NHLBI NIH HHS U01 HL071556NHLBI NIH HHS U01 HL072734NHLBI NIH HHS U01HL072734NHLBI NIH HHS U01 HL072735NHLBI NIH HHS U01HL072735NHLBI NIH HHS U01 HL072736NHLBI NIH HHS U01HL072736NHLBI NIH HHS U01 HL072737NHLBI NIH HHS U01HL072737
6 · The paper itself

Abstract

For people enrolled in Cardiovascular Outcomes in Renal Atherosclerotic Lesions (CORAL), we sought to examine whether variation exists in the baseline medical therapy of different geographic regions and if any variations in prescribing patterns were associated with physician specialty. Patients were grouped by location within the United States (US) and outside the US (OUS), which includes Canada, South America, Europe, South Africa, New Zealand, and Australia. When comparing US to OUS, participants in the US took fewer anti-hypertensive medications (1.9 ± 1.5 vs. 2.4 ± 1.4; P < .001) and were less likely to be treated with an angiotensin-converting enzyme inhibitor or angiotensin II receptor blocker (46% vs. 62%; P < .001), calcium channel antagonist (37% vs. 58%; P < .001), and statin (64% vs. 75%; P < .05). In CORAL, the identification of variations in baseline medical therapy suggests that substantial opportunities exist to improve the medical management of patients with atherosclerotic renal-artery stenosis.

Indexed as

AgedAntihypertensive AgentsAtherosclerosisCanadaDisease ManagementEuropeFemaleHumansHypertension, RenalInternationalityLinear ModelsMaleMedicineMiddle AgedMultivariate AnalysisNew ZealandAntihypertensive AgentsAntihypertensive medical therapygeographyrenovascular hypertension

Identifiers

PMID26051926
PMCPMC4460564
OpenAlexW1752351961

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.