ArticleCurrent biology : CB2015
Genomic signatures of cooperation and conflict in the social amoeba.
Article in Current biology : CB, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- The Evolutionary and Ecological Consequences of Cooperation.The American naturalist · 2026Review
- Cooperation and the evolution of bacterial niche breadth.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Hypermutable hotspot enables the rapid evolution of self/non-self recognition genes inProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Testing the coordination hypothesis: incompatibilities in aggregative development of an experimentally evolved social amoeba.Evolution letters · 2025Article
- Going against the family: Perturbation of a greenbeard pathway leads to falsebeard cheating.iScience · 2024Article
- The greenbeard gene tgrB1 regulates altruism and cheating in Dictyostelium discoideum.Nature communications · 2024Article
- Reduced social function in experimentally evolvedProceedings. Biological sciences · 2023Article
- SOCfinder: a genomic tool for identifying social genes in bacteria.Microbial genomics · 2023Article
- Open questions in the social lives of viruses.Journal of evolutionary biology · 2023Review
- Signatures of kin selection in a natural population of the bacteriaEvolution letters · 2023Article
- The evolution of manipulative cheating.eLife · 2022Article
- Kin selection for cooperation in natural bacterial populations.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- The evolution of cheating in viruses.Nature communications · 2021Review
- A Study of the Coevolution of Digital Organisms with an Evolutionary Cellular Automaton.Biology · 2021Article
- Cyclic AMP is dispensable for allorecognition in Dictyostelium cells overexpressing PKA-C.Journal of cell science · 2021Article
- Ten recent insights for our understanding of cooperation.Nature ecology & evolution · 2021Review
- Search for MHC/TCR-Like Systems in Living Organisms.Frontiers in immunology · 2021Article
- The Whi2p-Psr1p/Psr2p complex regulates interference competition and expansion of cells with competitive advantage in yeast colonies.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Loss of the Polyketide Synthase StlB Results in Stalk Cell Overproduction in Polysphondylium violaceum.Genome biology and evolution · 2020Article
- Variation at an adhesin locus suggests sociality in natural populations of the yeastProceedings. Biological sciences · 2019Article
Corrections and comments
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Authors and funding
26 authors.
Funding
Abstract
Cooperative systems are susceptible to invasion by selfish individuals that profit from receiving the social benefits but fail to contribute. These so-called "cheaters" can have a fitness advantage in the laboratory, but it is unclear whether cheating provides an important selective advantage in nature. We used a population genomic approach to examine the history of genes involved in cheating behaviors in the social amoeba Dictyostelium discoideum, testing whether these genes experience rapid evolutionary change as a result of conflict over spore-stalk fate. Candidate genes and surrounding regions showed elevated polymorphism, unusual patterns of linkage disequilibrium, and lower levels of population differentiation, but they did not show greater between-species divergence. The signatures were most consistent with frequency-dependent selection acting to maintain multiple alleles, suggesting that conflict may lead to stalemate rather than an escalating arms race. Our results reveal the evolutionary dynamics of cooperation and cheating and underscore how sequence-based approaches can be used to elucidate the history of conflicts that are difficult to observe directly.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.