Evidence map›Paper›PMID 26050648›Full record

ArticleLeukemia2016

The leukemia-associated RUNX1/ETO oncoprotein confers a mutator phenotype.

V J Forster, M H Nahari, N Martinez-Soria, A K Bradburn, A Ptasinska, S A Assi, S E Fordham, H McNeil, C Bonifer, O Heidenreich and 1 more

Open access · hybridAbstract readLetter
In one paragraph

Article in Leukemia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. RUNX1-ETO: Attacking the Epigenome for Genomic Instable Leukemia.International journal of molecular sciences · 2019
    Review
  14. Article
  15. Article
  16. Frontiers in cell and developmental biology · 2017
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

V J ForsterNorthern Institute for Cancer Research, Newcastle Cancer Centre, Newcastle University, Newcastle-upon-Tyne, UK.
M H NahariNorthern Institute for Cancer Research, Newcastle Cancer Centre, Newcastle University, Newcastle-upon-Tyne, UK.
N Martinez-SoriaNorthern Institute for Cancer Research, Newcastle Cancer Centre, Newcastle University, Newcastle-upon-Tyne, UK.
A K BradburnNorthern Institute for Cancer Research, Newcastle Cancer Centre, Newcastle University, Newcastle-upon-Tyne, UK.
A PtasinskaSchool of Cancer Sciences, Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
S A AssiSchool of Cancer Sciences, Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
S E FordhamNorthern Institute for Cancer Research, Newcastle Cancer Centre, Newcastle University, Newcastle-upon-Tyne, UK.
H McNeilNorthern Institute for Cancer Research, Newcastle Cancer Centre, Newcastle University, Newcastle-upon-Tyne, UK.
C BoniferSchool of Cancer Sciences, Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
O HeidenreichNorthern Institute for Cancer Research, Newcastle Cancer Centre, Newcastle University, Newcastle-upon-Tyne, UK.
J M AllanNorthern Institute for Cancer Research, Newcastle Cancer Centre, Newcastle University, Newcastle-upon-Tyne, UK.
Newcastle University · GBUniversity of Birmingham · GB

Funding

Medical Research Council MR/M009157/1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene FusionMutationCore Binding Factor Alpha 2 SubunitHumansLeukemia, Myeloid, AcuteMembrane ProteinsPhenotypeProto-Oncogene ProteinsRUNX1 Translocation Partner 1 ProteinTranscription FactorsCore Binding Factor Alpha 2 SubunitMembrane Proteinsphosphatidylinositol glycan-class A proteinProto-Oncogene ProteinsRUNX1 protein, humanRUNX1T1 protein, humanRUNX1 Translocation Partner 1 ProteinTranscription Factors

Identifiers

PMID26050648
PMCPMC4705432
OpenAlexW1883409482

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.