Evidence map›Paper›PMID 26050617›Full record

ArticleParasites & vectors2015

Response to Esteve-Gassent et al.: flaB sequences obtained from Texas PCR products are identical to the positive control strain Borrelia burgdorferi B31.

Steven J Norris, Alan G Barbour, Durland Fish, Maria A Diuk-Wasser

Open access · goldAbstract readLetterComment
In one paragraph

Article in Parasites & vectors, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Single Core Genome Sequencing for Detection of bothInternational journal of environmental research and public health · 2019
    Article
  4. Brave New Worlds: The Expanding Universe of Lyme Disease.Vector borne and zoonotic diseases (Larchmont, N.Y.) · 2017
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Steven J NorrisDepartments of Pathology & Laboratory Medicine and Microbiology and Molecular Genetics, University of Texas Medical School at Houston, PO Box 20708, 77225-0708, Houston, TX, USA. Steven.J.Norris@uth.tmc.edu.
Alan G BarbourDepartments of Microbiology and Molecular Genetics, Medicine, and Ecology and Evolutionary Biology, University of California at Irvine, Irvine, USA. abarbour@uci.edu.
Durland FishDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, USA. Durland.Fish@yale.edu.
Maria A Diuk-WasserDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, USA. maria.diuk@yale.edu.
Yale University · USUniversity of California, Irvine · US

Funding

Virulence Determinants of Borrelia burgdorferiR01AI059048 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI NORRIS, STEVEN J. · 2004 to 2016
$5.3M
NIAID NIH HHS R01 AI059048
6 · The paper itself

Abstract

Feria-Arroyo et al. had reported previously that, based on PCR analysis, 45% of Ixodes scapularis ticks collected in Texas and Mexico were infected with the Lyme disease spirochete Borrelia burgdorferi (Parasit. Vectors 2014, 7:199). However, our analyses of their initial data (Parasit. Vectors 2014, 7:467) and a recent response by Esteve-Gassent et al. (Parasit. Vectors 2015, 8:129) provide evidence that the positive PCR results obtained from both ribosomal RNA intergenic sequences and the flagellin gene flaB are highly likely due to contamination by the B. burgdorferi B31 positive control strain.

Indexed as

Animal DistributionAnimalsArthropod VectorsIxodesLyme Disease

Identifiers

PMID26050617
PMCPMC4489397
OpenAlexW1575010271

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.