Evidence map›Paper›PMID 26049700›Full record

ReviewCancer journal (Sudbury, Mass.)

Image-Guided Tumor Resection.

Julia Parrish-Novak, Eric C Holland, James M Olson

Open access · greenAbstract readReview
In one paragraph

Review in Cancer journal (Sudbury, Mass.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Imaging skins: stretchable Gd2O2S:Tb X-ray detectors for image-guided surgery.International journal of computer assisted radiology and surgery · 2026
    Article
  3. Article
  4. Article
  5. Precise Diagnosis and Therapy of Bone Cancer Using Near-Infrared Lights.Frontiers in bioengineering and biotechnology · 2021
    Review
  6. Article
  7. Article
  8. Article
  9. [Theranostics · 2018
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Julia Parrish-NovakFrom the *Research and Project Management, Blaze Bioscience, Inc; †Human Biology Division, Fred Hutchinson Cancer Research Center; and ‡Fred Hutchinson Cancer Research Center, Seattle, WA.
Eric C Holland
James M Olson
Blaze Bioscience (United States) · USCancer Research Center · USFred Hutch Cancer Center · US

Funding

Testing a cancer patient-specific SARS-CoV-2 vaccine in chemotherapy- and radiation-treated pediatric brain tumor mouse modelsR01CA114567 · NCI · SEATTLE CHILDREN'S HOSPITAL · PI OLSON, JAMES M · 2006 to 2023
$4.9M
Chlorotoxin as a Targeting Agent for Cancer TherapiesR01CA135491 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI OLSON, JAMES M · 2008 to 2018
$3.8M
NCI NIH HHS HHSN261201200054CNCI NIH HHS R01 CA114567NCI NIH HHS R01 CA135491NCI NIH HHS R01CA135491
6 · The paper itself

Abstract

Each year, millions of individuals undergo cancer surgery that is intended to be curative or at least a necessary component of a curative regimen. Particularly for those patients whose cancer harbors cells that are resistant to chemotherapy or radiation, the extent of surgery often defines whether they will be a survivor or casualty of the disease. For many solid tumor types, the difference in survival between patients who undergo gross total resection and those who have residual bulky disease is often profound. With surgery being central to cancer survivorship, it is stunning how few resources have been invested in improving surgical outcomes, particularly in comparison to chemotherapeutic research and discovery. This article reviews recent advances related to developing targeted fluorescent agents to guide surgeons during cancer removal. The goal of these drugs and devices is to clearly distinguish cancer from normal tissue to improve surgical outcome for cancer patients.

Indexed as

Surgery, Computer-AssistedFluorescent DyesHumansNeoplasmsRadiographyFluorescent Dyes

Identifiers

PMID26049700
PMCPMC4459523
OpenAlexW2413847658

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.