Evidence map›Paper›PMID 26049592›Full record

ArticleVeterinary microbiology2015

Characterisation of a mobilisable plasmid conferring florfenicol and chloramphenicol resistance in Actinobacillus pleuropneumoniae.

Janine T Bossé, Yanwen Li, Tom G Atherton, Stephanie Walker, Susanna M Williamson, Jon Rogers, Roy R Chaudhuri, Lucy A Weinert, Matthew T G Holden, Duncan J Maskell and 5 more

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Veterinary microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 42 citations in OpenAlex.

  1. Trial
  2. From Metagenomes to Functional Expression of Resistance:Antibiotics (Basel, Switzerland) · 2025
    Article
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  4. Article
  5. Article
  6. Article
  7. Comparative Genome Sequence Analysis ofFrontiers in microbiology · 2021
    Article
  8. Article
  9. Comparative Genomics ofInternational journal of genomics · 2020
    Article
  10. Article
  11. Antimicrobial Resistance inMicrobiology spectrum · 2018
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

  • Erratum issued
    BRaDP1T consortium [added]
5 · Who and what money

Authors and funding

15 authors at 6 institutions in 1 country.

Janine T BosséSection of Paediatrics, Department of Medicine, Imperial College London, St. Mary's Campus, London, W2 1PG, UK. Electronic address: j.bosse@imperial.ac.uk.
Yanwen LiSection of Paediatrics, Department of Medicine, Imperial College London, St. Mary's Campus, London, W2 1PG, UK.
Tom G AthertonSection of Paediatrics, Department of Medicine, Imperial College London, St. Mary's Campus, London, W2 1PG, UK.
Stephanie WalkerSection of Paediatrics, Department of Medicine, Imperial College London, St. Mary's Campus, London, W2 1PG, UK.
Susanna M WilliamsonAnimal and Plant Health Agency (APHA) Bury St Edmunds, Rougham Hill, Bury St Edmunds, Suffolk, IP33 2RX, UK.
Jon RogersAnimal and Plant Health Agency (APHA) Bury St Edmunds, Rougham Hill, Bury St Edmunds, Suffolk, IP33 2RX, UK.
Roy R ChaudhuriDepartment of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge, CB3 0ES, UK.
Lucy A WeinertDepartment of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge, CB3 0ES, UK.
Matthew T G HoldenThe Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.
Duncan J MaskellDepartment of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge, CB3 0ES, UK.
Alexander W TuckerDepartment of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge, CB3 0ES, UK.
Brendan W WrenFaculty of Infectious & Tropical Diseases, London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.
Andrew N RycroftDepartment of Pathology and Pathogen Biology, The Royal Veterinary College, Hawkshead Campus, Hatfield, Hertfordshire, AL9 7TA, UK.
Paul R LangfordSection of Paediatrics, Department of Medicine, Imperial College London, St. Mary's Campus, London, W2 1PG, UK. Electronic address: p.langford@imperial.ac.uk.
BRaDP1T consortium
Imperial College London · GBUniversity of Cambridge · GBAnimal and Plant Health Agency · GBRoyal Veterinary College · GBUniversity of London · GBWellcome Sanger Institute · GB

Funding

Biotechnology and Biological Sciences Research Council BB/G018553/1Biotechnology and Biological Sciences Research Council BB/G019177/1Biotechnology and Biological Sciences Research Council BB/G019274/1Biotechnology and Biological Sciences Research Council BB/G020744/1
6 · The paper itself

Abstract

The complete nucleotide sequence of a 7.7kb mobilisable plasmid (pM3446F), isolated from a florfenicol resistant isolate of Actinobacillus pleuropneumoniae, showed extended similarity to plasmids found in other members of the Pasteurellaceae containing the floR gene as well as replication and mobilisation genes. Mobilisation into other Pasteurellaceae species confirmed that this plasmid can be transferred horizontally.

Indexed as

Actinobacillus InfectionsActinobacillus pleuropneumoniaeAnimalsBase SequenceChloramphenicol ResistanceDrug Resistance, BacterialMolecular Sequence DataPasteurellaceaePasteurellaceae InfectionsPlasmidsSequence Analysis, DNASwineSwine DiseasesThiamphenicolflorfenicolThiamphenicol

Identifiers

PMID26049592
PMCPMC4503812
OpenAlexW1878824442

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.