Evidence map›Paper›PMID 26049543›Full record

ArticleAIDS (London, England)2015

Disclosure of their HIV status to perinatally infected youth using the adapted Blasini disclosure model in Haiti and the Dominican Republic: preliminary results.

Consuelo M Beck-Sagué, Jessy Dévieux, Maria Claudia Pinzón-Iregui, Leonel Lerebours-Nadal, Rosa Abreu-Pérez, Rachel Bertrand, Vanessa Rouzier, Stephanie Gaston, Gladys Ibanez, Mina Halpern and 6 more

Abstract readComparative StudyControlled Clinical Trial
In one paragraph

Article in AIDS (London, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 4 countries.

Consuelo M Beck-SaguéaRobert Stempel College of Public Health and Social Work, Florida International University, Miami, Florida, USA bClínica de Familia La Romana, Dominican Republic cRobert Reid Cabral Children's Hospital, Santo Domingo, Dominican Republic dGroupe Haïtien d'Etude du Sarcome de Kaposi et des Infections Opportunistes (GHESKIO) Centres, Port-au-Prince, Haïti eCornell University School of Medicine, New York fVoluntary Faculty, University of Miami Miller School of Medicine, Miami, Florida gColumbia University College of Physicians and Surgeons, New York, USA hUniversity of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico.
Jessy Dévieux
Maria Claudia Pinzón-Iregui
Leonel Lerebours-Nadal
Rosa Abreu-Pérez
Rachel Bertrand
Vanessa Rouzier
Stephanie Gaston
Gladys Ibanez
Mina Halpern
Jean W Pape
Patricia Dorceus
Sharice M Preston
Andrew G Dean
Stephen W Nicholas
Ileana Blasini
Florida International University · USGheskio Centers · HTColumbia University · USHospital Infantil Dr. Robert Reid Cabral · DOUniversity of Miami · USUniversity of Puerto Rico, Medical Sciences Campus · PR

Funding

Piloting disclosure of their status to youth living with HIV in HispaniolaR21HD074240 · NICHD · FLORIDA INTERNATIONAL UNIVERSITY · PI BECK-SAGUE, CONSUELO MARIA · 2012 to 2013
$343k
NICHD NIH HHS R21 HD074240NICHD NIH HHS R21HD074240
6 · The paper itself

Abstract

objectivesTo assess the safety, acceptability, and preliminary efficacy of a culturally-adapted disclosure intervention for perinatally HIV-infected combined antiretroviral therapy patients in Haiti and the Dominican Republic.

designA quasi-experimental trial was conducted comparing caregiver-youth pairs who completed the intervention [adapted Blasini disclosure model (aBDM)] to pairs who discontinued aBDM participation before disclosure. aBDM consists of five components: structured healthcare worker training; one-on one pre-disclosure intervention/education sessions for youth (describing pediatric chronic diseases including cancer, diabetes and HIV) and for caregivers (strengthening capacity for disclosure); a scheduled supportive disclosure session; and one-on-one postdisclosure support for caregivers and youth.

methodsCaregivers of nondisclosed combined antiretroviral therapy patients aged 10.0-17.8 years were invited to participate. Data were collected by separate one-on-one face-to-face interviews of caregivers and youth by study staff and medical record review by pediatricians at enrollment and 3 months after disclosure or after intervention discontinuation.

resultsTo date, 65 Dominican Republic and 27 Haiti caregiver-youth pairs have enrolled. At enrollment, only 46.4% of youth had viral suppression and 43.4% of caregivers had clinically significant depressive symptomatology. To date, two serious study-related adverse events have occurred. Seven of the 92 (7.6%, 6 in the Dominican Republic) enrolled pairs discontinued participation before disclosure and 39 had completed postdisclosure participation. Median plasma HIV-RNA concentration was lower in youth who completed aBDM than in youth who discontinued participation before aBDM disclosure (<40 versus 8673 copies/ml; P = 0.027). Completers expressed considerable satisfaction with aBDM.

conclusionPreliminary results suggest safety, acceptability, and possible effectiveness of the aBDM.

Indexed as

HIV InfectionsModels, PsychologicalTruth DisclosureAdolescentAnti-Retroviral AgentsCaregiversChildDominican RepublicFemaleHaitiHumansMalePatient SatisfactionAnti-Retroviral Agents

Identifiers

PMID26049543
PMCPMC4596258
OpenAlexW622317993

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.