ArticleCerebral cortex (New York, N.Y. : 1991)2015
A Diffusion MRI Tractography Connectome of the Mouse Brain and Comparison with Neuronal Tracer Data.
Article in Cerebral cortex (New York, N.Y. : 1991), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 135 papers, 5 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
135 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Considerations and recommendations from the ISMRM diffusion study group for preclinical diffusion MRI: Part 2-Ex vivo imaging: Added value and acquisition.Magnetic resonance in medicine · 2025Guideline
- A systematic review of the relationship between magnetic resonance imaging based resting-state and structural networks in the rodent brain.Frontiers in neuroscience · 2023Pooled it
- Tractography reproducibility challenge with empirical data (TraCED): The 2017 ISMRM diffusion study group challenge.Journal of magnetic resonance imaging : JMRI · 2020Pooled it
- A systematic review on the quantitative relationship between structural and functional network connectivity strength in mammalian brains.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019Pooled it
- Histological methods for ex vivo axon tracing: A systematic review.Neurological research · 2016Pooled it
- Diffusion MRI reveals amyloid plaque-associated cellular signatures through spatial transcriptomic integration.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Thiol-Based Neuroprotective Copolymers Acutely Restore Redox Metabolism and Mediate Vasogenic Edema in a Mouse Model of Traumatic Brain Injury.Macromolecular bioscience · 2026Article
- Protocol for diffusion magnetic resonance imaging and tractography in ex vivo mouse models.STAR protocols · 2026Article
- Developmental human brain connectome from fetal stage to early childhood.Developmental cognitive neuroscience · 2026Review
- Detecting early brain susceptibility changes before demyelination in cuprizone mouse model using quantitative susceptibility mapping (QSM).NeuroImage · 2026Article
- Mouse white matter matters: cortical origins and spatial organization of mouse white matter tracts.Brain structure & function · 2026Article
- Directed connectomes across species reveal conserved and divergent pathways of neural signaling.bioRxiv : the preprint server for biology · 2025Article
- Evolution of the Rich Club Properties in Mouse, Macaque, and Human Brain Networks: A Study of Functional Integration, Segregation, and Balance.Neuroscience bulletin · 2025Article
- Olfactory-Guided Behavior Uncovers Imaging and Molecular Signatures of Alzheimer's Disease Risk.Brain sciences · 2025Article
- Smelling the Risk: Early Olfactory Deficits, Brain Networks, and Blood Markers of Alzheimer's Disease Risk in Humanized APOE Mice.bioRxiv : the preprint server for biology · 2025Article
- The Duke Mouse Brain Atlas: MRI and light sheet microscopy stereotaxic atlas of the mouse brain.Science advances · 2025Article
- From Circuits to Lifespan: Translating Mouse and Human Timelines with Neuroimaging-Based Tractography.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Neurotransmitters' white matter mapping unveils the neurochemical fingerprints of stroke.Nature communications · 2025Article
- Individualized mouse brain network models produce asymmetric patterns of functional connectivity after simulated traumatic injury.Network neuroscience (Cambridge, Mass.) · 2025Article
- Multiscale comparative connectomics.Imaging neuroscience (Cambridge, Mass.) · 2025Article
75 more citing papers are in PubMed but not listed here.
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5 authors.
Funding
Abstract
Interest in structural brain connectivity has grown with the understanding that abnormal neural connections may play a role in neurologic and psychiatric diseases. Small animal connectivity mapping techniques are particularly important for identifying aberrant connectivity in disease models. Diffusion magnetic resonance imaging tractography can provide nondestructive, 3D, brain-wide connectivity maps, but has historically been limited by low spatial resolution, low signal-to-noise ratio, and the difficulty in estimating multiple fiber orientations within a single image voxel. Small animal diffusion tractography can be substantially improved through the combination of ex vivo MRI with exogenous contrast agents, advanced diffusion acquisition and reconstruction techniques, and probabilistic fiber tracking. Here, we present a comprehensive, probabilistic tractography connectome of the mouse brain at microscopic resolution, and a comparison of these data with a neuronal tracer-based connectivity data from the Allen Brain Atlas. This work serves as a reference database for future tractography studies in the mouse brain, and demonstrates the fundamental differences between tractography and neuronal tracer data.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.