Evidence map›Paper›PMID 26048703›Full record

ReviewAnnual review of nutrition2015

Stable Isotope Ratios as Biomarkers of Diet for Health Research.

Diane M O'Brien

Abstract readReview
In one paragraph

Review in Annual review of nutrition, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed.

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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Diane M O'BrienCenter for Alaska Native Health Research, Institute of Arctic Biology and Department of Biology and Wildlife, University of Alaska, Fairbanks, Alaska 99775-7000; email: dmobrien@alaska.edu.

Funding

YUP'IK PERCEPTIONS OF BODY WEIGHT AND DIABETESP20RR016430 · NCRR · UNIVERSITY OF ALASKA FAIRBANKS · PI BERSAMIN, ANDREA · 2001 to 2011
$23.4M
Pharmacogenetics in Rural and Underserved PopulationsU01GM092676 · NIGMS · UNIVERSITY OF WASHINGTON · PI BURKE, WYLIE G., THUMMEL, KENNETH E. · 2010 to 2014
$9.9M
Pilot Project ProgramP30GM103325 · NIGMS · UNIVERSITY OF ALASKA FAIRBANKS · PI BERSAMIN, ANDREA · 2012 to 2016
$5.3M
Validating Multiple Stable Isotope Measures of Diet in the NPAAS Feeding StudyR21CA182674 · NCI · UNIVERSITY OF ALASKA FAIRBANKS · PI O'BRIEN, DIANE MARIE · 2014 to 2015
$379k
NCI NIH HHS R21 CA182674NCRR NIH HHS P20 RR016430NIGMS NIH HHS P30 GM103325NIGMS NIH HHS U01 GM092676
6 · The paper itself

Abstract

Diet is a leading modifiable risk factor for chronic disease, but it remains difficult to measure accurately due to the error and bias inherent in self-reported methods of diet assessment. Consequently, there is a pressing need for more objective biomarkers of diet for use in health research. The stable isotope ratios of light elements are a promising set of candidate biomarkers because they vary naturally and reproducibly among foods, and those variations are captured in molecules and tissues with high fidelity. Recent studies have identified valid isotopic measures of short- and long-term sugar intake, meat intake, and fish intake in specific populations. These studies provide a strong foundation for validating stable isotopic biomarkers in the general US population. Approaches to improve specificity for specific foods are needed; for example, by modeling intake using multiple stable isotope ratios or by isolating and measuring specific molecules linked to foods of interest.

Indexed as

DietAnimalsBiomarkersBiomedical ResearchCarbon IsotopesDietary SucroseEuropeFishesFoodFood AnalysisHumansHydrogenIsotopesMass SpectrometryMeatNitrogen IsotopesBiomarkersCarbon IsotopesDietary SucroseHydrogenIsotopesNitrogen IsotopesOxygen IsotopesSulfur Isotopescarbon-13isotope ratio mass spectrometrynitrogen-15nutritional epidemiologysulfur-34

Identifiers

PMID26048703
PMCPMC4791982

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.