Evidence map›Paper›PMID 26048625›Full record

ArticleRheumatology international2015

The impact of concomitant diffuse idiopathic skeletal hyperostosis on the achievement of minimal disease activity in subjects with psoriatic arthritis.

Nicola Pappone, Matteo Nicola Dario Di Minno, Salvatore Iervolino, Roberta Lupoli, Reuven Mader, Carmela Zincarelli, Rosario Peluso

Abstract read
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Article in Rheumatology international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Nicola PapponeRheumatology and Rehabilitation Research Unit, "Salvatore Maugeri" Foundation I.R.C.C.S. Scientific Institute of Telese Terme, Via Bagni Vecchi 1, Telese Terme, BN, Italy.
Matteo Nicola Dario Di MinnoDepartment of Clinical Medicine and Surgery, Federico II University, Naples, Italy.
Salvatore IervolinoRheumatology and Rehabilitation Research Unit, "Salvatore Maugeri" Foundation I.R.C.C.S. Scientific Institute of Telese Terme, Via Bagni Vecchi 1, Telese Terme, BN, Italy. calmodulina@inwind.it.
Roberta LupoliDepartment of Clinical Medicine and Surgery, Federico II University, Naples, Italy.
Reuven MaderRheumatic Diseases Unit, Ha'Emek Medical Center, Afula, Israel.
Carmela ZincarelliRheumatology and Rehabilitation Research Unit, "Salvatore Maugeri" Foundation I.R.C.C.S. Scientific Institute of Telese Terme, Via Bagni Vecchi 1, Telese Terme, BN, Italy.
Rosario PelusoDepartment of Clinical Medicine and Surgery, Federico II University, Naples, Italy.
Federico II University Hospital · ITFondazione Salvatore Maugeri · ITEmek Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diffuse idiopathic skeletal hyperostosis (DISH) is characterized by ossification of different entheses. Psoriatic arthritis (PsA) is a seronegative spondyloarthritis associated with psoriasis. Given the possible overlap of the two diseases, we assessed whether DISH presence may affect PsA clinical outcomes. Also, predictors of DISH presence in the cohort were investigated. Consecutive PsA patients from two Italian Rheumatology Research Units were enrolled. Subjects were splitted into two groups, according to the current treatment (TNF-α blockers or traditional DMARDs). All patients underwent a rheumatologic examination, blood sample collections and spine radiographs. Information about traditional vascular risk factors was recorded. In each patient, the presence of minimal disease activity was evaluated and the presence of DISH was established according to the Resnick and Niwayama criteria. Among the 80 enrolled subjects (57.5 % men, mean age 56.5 ± 11.1 years), the overall prevalence of DISH was 30.0 %. Patients with DISH were older, with higher BMI and waist circumference. DISH subjects showed worsen BASMI, HAQ and ESR. In a multivariate regression model, BASMI was a significant predictor of DISH presence (OR 3.027, 95 % CI 1.449-6.325, p = 0.003). The prevalence of MDA was lower in DISH patients than in no-DISH (16.7 vs 41.1 %, p = 0.041), and the presence of DISH was a predictor of not achieving MDA (OR 3.485, 95 % CI 1.051-11.550, p = 0.041). PsA subjects with DISH showed worsen indices of spine mobility and articular function and lower prevalence of minimal disease activity than no-DISH patients.

Indexed as

AdultAgedAntirheumatic AgentsArthritis, PsoriaticFemaleHumansHyperostosis, Diffuse Idiopathic SkeletalMaleMiddle AgedRange of Motion, ArticularSpineTreatment OutcomeTumor Necrosis Factor-alphaAntirheumatic AgentsTumor Necrosis Factor-alphaDiffuse idiopathic skeletal hyperostosisMinimal disease activityPsoriatic arthritis

Identifiers

PMID26048625
OpenAlexW563668921

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.