Evidence map›Paper›PMID 26048076›Full record

ArticleJournal of biomedical informatics2015

Summarizing and visualizing structural changes during the evolution of biomedical ontologies using a Diff Abstraction Network.

Christopher Ochs, Yehoshua Perl, James Geller, Melissa Haendel, Matthew Brush, Sivaram Arabandi, Samson Tu

Abstract read
In one paragraph

Article in Journal of biomedical informatics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Big knowledge visualization of the COVID-19 CIDO ontology evolution.BMC medical informatics and decision making · 2023
    Article
  3. Review
  4. Article
  5. An empirical analysis of ontology reuse in BioPortal.Journal of biomedical informatics · 2017
    Article
  6. Article
  7. Article
  8. Article
  9. Tracking the Remodeling of SNOMED CT's Bacterial Infectious Diseases.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2016
    Article
  10. Evolution of biomedical ontologies and mappings: Overview of recent approaches.Computational and structural biotechnology journal · 2016
    Review
  11. Modelling Medications for Public Health Research.Online journal of public health informatics · 2016
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Christopher OchsComputer Science Department, New Jersey Institute of Technology, Newark, NJ 07102, USA. Electronic address: cro3@njit.edu.
Yehoshua PerlComputer Science Department, New Jersey Institute of Technology, Newark, NJ 07102, USA.
James GellerComputer Science Department, New Jersey Institute of Technology, Newark, NJ 07102, USA.
Melissa HaendelDepartment of Medical Informatics & Clinical Epidemiology, Oregon Health & Science University, Portland, OR 97239, USA.
Matthew BrushDepartment of Medical Informatics & Clinical Epidemiology, Oregon Health & Science University, Portland, OR 97239, USA.
Sivaram ArabandiONTOPRO, Houston, TX 77025, USA.
Samson TuStanford Center for Biomedical Informatics Research, Stanford University, Stanford, CA 94305, USA.

Funding

A family-based framework of quality assurance for biomedical ontologiesR01CA190779 · NCI · NEW JERSEY INSTITUTE OF TECHNOLOGY · PI PERL, YEHOSHUA · 2015 to 2017
$1.8M
NCI NIH HHS R01 CA190779NCI NIH HHS R01CA190779
6 · The paper itself

Abstract

Biomedical ontologies are a critical component in biomedical research and practice. As an ontology evolves, its structure and content change in response to additions, deletions and updates. When editing a biomedical ontology, small local updates may affect large portions of the ontology, leading to unintended and potentially erroneous changes. Such unwanted side effects often go unnoticed since biomedical ontologies are large and complex knowledge structures. Abstraction networks, which provide compact summaries of an ontology's content and structure, have been used to uncover structural irregularities, inconsistencies and errors in ontologies. In this paper, we introduce Diff Abstraction Networks ("Diff AbNs"), compact networks that summarize and visualize global structural changes due to ontology editing operations that result in a new ontology release. A Diff AbN can be used to support curators in identifying unintended and unwanted ontology changes. The derivation of two Diff AbNs, the Diff Area Taxonomy and the Diff Partial-area Taxonomy, is explained and Diff Partial-area Taxonomies are derived and analyzed for the Ontology of Clinical Research, Sleep Domain Ontology, and eagle-i Research Resource Ontology. Diff Taxonomy usage for identifying unintended erroneous consequences of quality assurance and ontology merging are demonstrated.

Indexed as

Biological OntologiesVocabulary, ControlledAlgorithmsBiomedical ResearchData CollectionDrug DesignQuality ControlSleepSoftwareTechnologyAbstraction networksOntology diffOntology quality assuranceOntology version changeSummarizing ontology changeSummarizing ontology evolutionVisualizing ontology evolution

Identifiers

PMID26048076
PMCPMC4532611

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.